ArticleNeuron2020
Arousal Modulates Retinal Output.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed.
- Awake alpha bursting emerges as the dynamic working state in a lateral geniculate thalamocortical cell model.PLoS computational biology · 2026Article
- Inferring brain-wide interactions using data-constrained recurrent neural network models.Neuron · 2026Article
- Pupil Constriction Causes Activity in the Human Retina and Visual System.Psychophysiology · 2026Article
- Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.Nature reviews. Neuroscience · 2026Review
- Large-scale electrophysiology at single-spike resolution.Nature reviews. Neuroscience · 2026Review
- Categorization is 'baked' into the brain.Nature reviews. Neuroscience · 2026Review
- A hierarchical electrical synaptic circuit mechanism for integrative parallel visual processing in the retina.Neuron · 2026Article
- Action potential propagation in the rodent myelinated optic nerve does not trigger neurovascular coupling.Nature communications · 2026Article
- The functional organization of retinal input to the mouse superior colliculus.bioRxiv : the preprint server for biology · 2026Article
- Behavioural states control binocular vision through input-specific mechanisms.Nature communications · 2026Article
- Subunit-specific behavioral modulation of sensory tuning in the visual cortex.PLoS computational biology · 2026Article
- Convergence of Cortical and Thalamic Origins of Free Behavior Modulation of Mouse Primary Visual Cortex.bioRxiv : the preprint server for biology · 2026Article
- Mapping the visual cortex with Zebra noise and wavelets.Journal of vision · 2026Article
- Trait-like visual cortical hyperactivity in trait anxiety.Nature communications · 2025Article
- Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings.Neuron · 2025Article
- The central histaminergic system slows visual processing in the retina and lateral geniculate nucleus of awake mice.PLoS biology · 2025Article
- When the brain talks back to the eye.PLoS biology · 2025Article
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- Pupil size modulation drives retinal activity in mice and shapes human perception.Nature communications · 2025Article
- Behavioral Modulation and Molecular Definition of Wide-Field Vertical Cells in the Mouse Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
16 more citing papers are in PubMed but not listed here.
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8 authors.
Funding
Abstract
At various stages of the visual system, visual responses are modulated by arousal. Here, we find that in mice this modulation operates as early as in the first synapse from the retina and even in retinal axons. To measure retinal activity in the awake, intact brain, we imaged the synaptic boutons of retinal axons in the superior colliculus. Their activity depended not only on vision but also on running speed and pupil size, regardless of retinal illumination. Arousal typically reduced their visual responses and selectivity for direction and orientation. Recordings from retinal axons in the optic tract revealed that arousal modulates the firing of some retinal ganglion cells. Arousal had similar effects postsynaptically in colliculus neurons, independent of activity in the other main source of visual inputs to the colliculus, the primary visual cortex. These results indicate that arousal modulates activity at every stage of the mouse visual system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.