Evidence map›Paper›PMID 32445515›Full record

ArticleNMR in biomedicine2020

Rapid volumetric gagCEST imaging of knee articular cartilage at 3 T: evaluation of improved dynamic range and an osteoarthritic population.

Lauren E Watkins, Elka B Rubin, Valentina Mazzoli, Scott D Uhlrich, Arjun D Desai, Marianne Black, Gabe K Ho, Scott L Delp, Marc E Levenston, Gary S Beaupré and 2 more

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Advances in cartilage imaging techniques.Nature reviews. Rheumatology · 2026
    Review
  3. [EJNMMI research · 2025
    Article
  4. Review
  5. Magma (New York, N.Y.) · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Lauren E WatkinsBioengineering, Stanford University, Stanford, California, USA.ORCID 0000-0003-3592-4089
Elka B RubinRadiology, Stanford University, Stanford, California, USA.
Valentina MazzoliRadiology, Stanford University, Stanford, California, USA.
Scott D UhlrichMechanical Engineering, Stanford University, Stanford, California, USA.
Arjun D DesaiElectrical Engineering, Stanford University, Stanford, California, USA.
Marianne BlackRadiology, Stanford University, Stanford, California, USA.
Gabe K HoBioengineering, Stanford University, Stanford, California, USA.
Scott L DelpBioengineering, Stanford University, Stanford, California, USA.
Marc E LevenstonBioengineering, Stanford University, Stanford, California, USA.
Gary S BeaupréBioengineering, Stanford University, Stanford, California, USA.
Garry E GoldBioengineering, Stanford University, Stanford, California, USA.
Feliks KoganRadiology, Stanford University, Stanford, California, USA.
Stanford University · USUniversity Radiology · USStanford Medicine · USVA Palo Alto Health Care System · US

Funding

Rapid MRI for Evaluation of OsteoarthritisR01EB002524 · NIBIB · STANFORD UNIVERSITY · PI Akshay Chaudhari, Garry E Gold · 2003 to 2026
$10.1M
Advanced MR Imaging of Early OsteoarthritisK24AR062068 · NIAMS · STANFORD UNIVERSITY · PI GOLD, GARRY E · 2012 to 2022
$1.7M
Quantitative Assessment of Early Metabolic and Biochemical Changes in OsteoarthritisR00EB022634 · NIBIB · STANFORD UNIVERSITY · PI KOGAN, FELIKS · 2019 to 2021
$730k
Personalized Gait Training with Feedback to Reduce Knee Pain from OsteoarthritisI01RX001811 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI KOLESAR, JULIE ANN · 2016 to 2021
–
NIAMS NIH HHS K24 AR062068NIBIB NIH HHS R00 EB022634NIBIB NIH HHS R01 EB002524RRD VA I01 RX001811
6 · The paper itself

Abstract

Chemical exchange saturation transfer of glycosaminoglycans, gagCEST, is a quantitative MR technique that has potential for assessing cartilage proteoglycan content at field strengths of 7 T and higher. However, its utility at 3 T remains unclear. The objective of this work was to implement a rapid volumetric gagCEST sequence with higher gagCEST asymmetry at 3 T to evaluate its sensitivity to osteoarthritic changes in knee articular cartilage and in comparison with T

Indexed as

GlycosaminoglycansAdultAgedCartilage, ArticularFemaleFemurHealthy VolunteersHumansKnee JointMagnetic Resonance ImagingMaleMiddle AgedOsteoarthritis, KneeProteoglycansReproducibility of ResultsGlycosaminoglycansProteoglycanscartilageCESTgagCESThuman studykneeosteoarthritis

Identifiers

PMID32445515
PMCPMC7347437
OpenAlexW3027681465

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.