ArticleMedical science monitor : international medical journal of experimental and clinical research2020
Determinants of Brachial-Ankle Pulse Wave Velocity and Vascular Aging in Healthy Older Subjects.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Association between the triglyceride-glucose-body mass index and the risk of early vascular aging in young and middle-aged Chinese adults: a cross-sectional study.BMC cardiovascular disorders · 2026Observational
- The modifying effect of chronological age on the predictive value of vascular aging indicators for the long-term cardiovascular events risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Clinical effects of Yiqi-Yangyin-Huoxue granules in the management of type 2 diabetes mellitus and early vascular aging: a randomized, double-blind, placebo-controlled trial protocol.Frontiers in medicine · 2026Article
- Iatrogenic coronary artery dissection: detection, management, and prevention.Frontiers in cardiovascular medicine · 2026Review
- Association between serum 25-hydroxyvitamin D levels and Early Vascular Aging in young and middle-aged adults.PloS one · 2026Article
- Comparison between vascular age based on brachial-ankle pulse wave velocity or carotid-femoral pulse wave velocity.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Beneficial Effects of Water-Based Exercise Alone and in Combination with Cognitive Training on Cardiovascular Fitness and Arterial Stiffness in Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial.Life (Basel, Switzerland) · 2025Article
- Discrepancies between general and central obesity in arterial stiffness: observational studies and Mendelian randomization study.BMC medicine · 2024Observational
- Association between brachial-ankle pulse wave velocity and the risk of new-onset atrial fibrillation: A report from Kailuan prospective cohort study.NPJ cardiovascular health · 2024Article
- Arterial stiffness expressed as brachial-ankle pulse wave velocity and gait assessment independent of lower extremity strength: a cross-sectional study in the older men population.Journal of geriatric cardiology : JGC · 2023Article
- Vascular Aging: Assessment and Intervention.Clinical interventions in aging · 2023Review
- Longitudinal association between cardiovascular health and arterial stiffness in the Chinese adult population.The Journal of international medical research · 2021Article
- Use of lipid parameters to identify apparently healthy men at high risk of arterial stiffness progression.BMC cardiovascular disorders · 2021Article
- Development and Validation of a Prediction Model for Elevated Arterial Stiffness in Chinese Patients With Diabetes Using Machine Learning.Frontiers in physiology · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Vascular aging is characterized by increasing arterial stiffness as measured by pulse wave velocity. The present study evaluated the factors influencing vascular aging in Chinese healthy older subjects. MATERIAL AND METHODS Disease- and treatment-free aged (≥60 years) participants were recruited from 2014 to 2019. Cardiometabolic risk factors and brachial-ankle pulse wave velocity (baPWV) were assessed. We defined healthy vascular aging (HVA) as the lowest 10% and early vascular aging (EVA) as the highest 10% of the baPWV distribution, after adjustment for age and blood pressure (BP). We fitted linear and logistic regression models to assess the determinants. RESULTS In all, 794 subjects (mean age 66.5±6.8 years, 71.0% male) were recruited; the 10th and 90th percentiles of baPWV were 1278 cm/s and 1955 cm/s, respectively. Age, BP, heart rate, and triglycerides were all positively associated with baPWV, whereas male subjects and body mass index (BMI) were negatively associated with baPWV. The number of participants diagnosed with either HVA or EVA was 80. Logistic regression models showed that sex, BMI, heart rate, and triglycerides were associated with HVA and EVA after adjustment for age, BP, and other confounding factors. CONCLUSIONS Male, high BMI, low heart rate, and low triglycerides are protective factors for vascular aging in the healthy aged population. Management of BMI, heart rate, triglycerides in a reasonable range may help to alleviate the vascular aging process.
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