ArticleJournal of veterinary internal medicine2020
Acute on chronic kidney disease in cats: Etiology, clinical and clinicopathologic findings, prognostic markers, and outcome.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- 2026 iCatCare consensus guidelines on the diagnosis and management of chronic kidney disease in cats.Journal of feline medicine and surgery · 2026Guideline
- Transforming growth factor-β in kidney disease in dogs and cats: a review of the evidence of its role in renal fibrosis.Journal of veterinary internal medicine · 2026Review
- Short-term mortality prediction based on biochemical blood markers in azotemic cattle with renal disease.Journal of veterinary internal medicine · 2026Article
- Association of obesity-related blood chemistry alterations with animal welfare outcomes in sterilized cats: A case-control study in Indonesia.Veterinary world · 2026Article
- Enhancing Detection of Feline Chronic Kidney Disease Through Smart Litter Box Monitoring.Animals : an open access journal from MDPI · 2026Article
- Understanding the Progression of Chronic Kidney Disease in Cats: From Pathophysiology to Emerging Biomarkers.Veterinary sciences · 2026Review
- Dogs and cats with acute-on-chronic kidney disease have worse outcomes than those with acute kidney injury following renal replacement therapy.Frontiers in veterinary science · 2026Article
- Feline Renal Cortical Thickness-Aortic Diameter Ratio in Healthy Versus Diseased Kidneys: Comparative Ultrasonographic Evaluation.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2025Article
- Exposure of Domestic Cats (Toxics · 2025Article
- A Review of Experimental Models of Feline Kidney Disease.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Review
- Pathological alteration and caspase-dependent activity of feline kidneys in natural infection of feline morbillivirus.BMC veterinary research · 2025Article
- Measurement of Insulin Resistance in Cats With Chronic Kidney Disease.Veterinary medicine and science · 2025Article
- Evaluation of urinary kidney injury molecule-1 in cats with chronic kidney disease.Journal of feline medicine and surgery · 2025Article
- Blood pressure and proteinuria in older cats and cats with chronic kidney disease.Veterinary world · 2025Article
- The clinical efficacy of cGMP-specific sildenafil on mitochondrial biogenesis induction and renal damage in cats with acute on chronic kidney disease.BMC veterinary research · 2024Article
- Supplementation of vitamin E as an addition to a commercial renal diet does not prolong survival of cats with chronic kidney disease.BMC veterinary research · 2024Article
- Evaluation of Disease Spectrum in Hospitalized Cats with Hyperlipasemia: Pancreatitis Alone Is Rare, Hyperlipasemia without Suspected Pancreatitis Is Common.Animals : an open access journal from MDPI · 2024Article
- Investigating the Efficacy of Kidney-ProtectiveAnimals : an open access journal from MDPI · 2024Article
- Occurrence of cardiovascular events in 168 cats with acute urinary tract obstruction.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Serum amyloid A in cats with renal azotemia.Veterinary world · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) and acute decompensation of CKD (ACKD) are common in cats.
objectivesTo characterize the etiology, clinical and clinicopathologic findings, and the short- and long-term prognosis of feline ACKD. ANIMALS: One hundred cats with ACKD.
methodsRetrospective study, search of medical records for cats with ACKD.
resultsCommon clinical signs included anorexia (85%), lethargy (60%), weight loss (39%), and vomiting (27%). Suspected etiologies included ureteral obstruction (11%), renal ischemia (9%), pyelonephritis (8%), others (6%), or unknown (66%). Hospitalization duration was longer in survivors versus nonsurvivors (median = 7 days, range = 2-26 versus median = 3 days, range = 2-20, respectively, P < .001). The survival rate to discharge was 58%. Age, serum creatinine, urea, and phosphorous concentrations were higher and venous blood pH was lower in nonsurvivors. However, only serum phosphorus remained associated with the short-term outcome in the multivariable model (P = .02; 95% confidence interval = 1.03-1.39). Survivors had a median survival time of 66 days after discharge. Serum creatinine concentrations at presentation as well as at discharge were associated with long-term survival (P < .002 for both).
conclusionsThe short-term prognosis of ACKD is comparable to acute kidney injury, while the long-term prognosis is guarded.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.