ArticlePediatric nephrology (Berlin, Germany)2020
Clinical and histological differences between adults and children in new onset IgA nephropathy.
Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Predictive role of Oxford Classification for prognosis in children with IgA nephropathy: a systematic review and meta-analysis.Renal failure · 2024Pooled it
- Examining the association between serum galactose-deficient IgA1 and primary IgA nephropathy: a systematic review and meta-analysis.Journal of nephrology · 2024Pooled it
- IgA nephropathy new therapies: from data in adults to application in children.Pediatric nephrology (Berlin, Germany) · 2026Review
- Transcriptomic Patterns in Adult and Pediatric Patients with IgA Nephropathy or IgA Vasculitis with Nephropathy.Journal of the American Society of Nephrology : JASN · 2025Article
- Bridging pediatric and adult IgAN: challenges in applying proteinuria-driven recommendations in the new IPNA guidelines.Pediatric nephrology (Berlin, Germany) · 2025Article
- Proteinuria Trajectory and Disease Progression in Children and Adults with IgA Nephropathy/Vasculitis.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Recent Developments in Pediatric Nephrology.Journal of clinical medicine · 2025Article
- Is Childhood IgA Nephropathy Different From Adult IgA Nephropathy? A Narrative Review.Canadian journal of kidney health and disease · 2025Review
- Are children with IgA nephropathy different from adult patients?Pediatric nephrology (Berlin, Germany) · 2024Article
- IgA nephropathy in children with minimal proteinuria: to biopsy or not to biopsy?Pediatric nephrology (Berlin, Germany) · 2024Article
- Factors related to recurrence of proteinuria in childhood IgA nephropathy.Pediatric nephrology (Berlin, Germany) · 2024Article
- A lack of KDIGO guidelines for adolescents and young adults with IgA nephropathy.Pediatric nephrology (Berlin, Germany) · 2024Review
- Corticosteroids in the treatment of IgA nephropathy: lessons from the TESTING trial.Pediatric nephrology (Berlin, Germany) · 2023Review
- Differences in response to treatment in children with severe IgA nephropathy according to patient age.Fukushima journal of medical science · 2023Article
- Urinary epidermal growth factor predicts complete remission of proteinuria in Chinese children with IgA nephropathy.Pediatric research · 2023Article
- How to take advantage of easily available biomarkers in patients with IgA nephropathy: IgA and C3 in serum and kidney biopsies.Pediatric nephrology (Berlin, Germany) · 2023Review
- Tertiary lymphoid tissues in kidney diseases: a perspective for the pediatric nephrologist.Pediatric nephrology (Berlin, Germany) · 2023Review
- Validation of the children international IgA nephropathy prediction tool based on data in Southwest China.Frontiers in pediatrics · 2023Article
- Chemokine (C-C motif) receptor 2 is associated with the pathological grade and inflammatory response in IgAN children.BMC nephrology · 2022Article
- Rare Collagenous Heterozygote Variants in Children With IgA Nephropathy.Kidney international reports · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious reports suggest initial presentation of IgA nephropathy (IgAN) in children is different from adults. No systematic comparison of clinical, biological, and histological childhood- and adult-onset IgAN is currently available.
methodsWe compared pediatric and adult clinical and histological characteristics at IgAN diagnosis. Data on 211 consecutive patients from two different centers in Paris (82 children, 129 adults) were reviewed. Kidney biopsies were scored for Oxford classification and podocytopathic (P1) features.
resultsWe report higher eGFR at diagnosis in children compared to adults (89.5 vs. 64 ml/min/1.73 m
conclusionProteinuria in children with IgAN is a marker of glomerular proliferative lesions whereas its presence in adults often reflects the presence of chronic lesions. This suggests the need for histological assessment.
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