Evidence map›Paper›PMID 32444832›Full record

ArticleScientific reports2020

Independent and combined effects of age, body mass index and gestational weight gain on the risk of gestational diabetes mellitus.

Heng Yaw Yong, Zalilah Mohd Shariff, Barakatun Nisak Mohd Yusof, Zulida Rejali, Yvonne Yee Siang Tee, Jacques Bindels, Eline M van der Beek

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 3 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Prediction Models for Maternal and Offspring Short- and Long-Term Outcomes Following Gestational Diabetes: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
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  4. Combined triple screening and BMI models for gestational diabetes prediction.Turkish journal of obstetrics and gynecology · 2026
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  12. LASSO regression-derived first-trimester (9-14Archives of gynecology and obstetrics · 2026
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Heng Yaw YongDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Zalilah Mohd ShariffDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia. zalilahms@upm.edu.my.
Barakatun Nisak Mohd YusofDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Zulida RejaliDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Yvonne Yee Siang TeeDanone Specialized Nutrition (Malaysia) Sdn Bhd, 59200, Mid Valley City, Lingkaran Syed Putra, Kuala Lumpur, Malaysia.
Jacques BindelsDanone Nutricia Research, Uppsalalaan 12, 3584, CT, Utrecht, The Netherlands.
Eline M van der BeekDanone Nutricia Research, Uppsalalaan 12, 3584, CT, Utrecht, The Netherlands.
Universiti Putra Malaysia · MYDanone (Netherlands) · NLJabatan Perkhidmatan Awam Malaysia · MYUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to identify the independent and combined effects of age, BMI at first prenatal visit and GWG on the risk of GDM. A retrospective cohort study of 1,951 pregnant women in Seremban district, Negeri Sembilan, Malaysia. GDM was defined as fasting plasma glucose (FPG) ≥5.6 mmol/l and/or 2-hour postprandial plasma glucose (2hPPG) ≥7.8 mmol/l. A higher percentage of women with GDM had 2 risk factors (29.0%) or >2 risk factors (8.6%) compared to non-GDM women (2 risk factors: 25.5%; >2 risk factors: 5.0%). In general, women with ≥2 risk factors were respectively 1.36-2.06 times more likely to have GDM compared to those without risk factors. Older maternal age and being overweight/obese were significantly associated with risk of GDM. Overweight/obese women with age ≥35 years had 2.45 times higher risk of GDM and having excessive GWG at second trimester further increased the risk of GDM. Age and BMI are independent risk factors for GDM but not GWG in the first and second trimester. The findings emphasize the need to focus on a healthy BMI before pregnancy and optimal GWG during pregnancy to improve pregnancy outcomes.

Indexed as

Body Mass IndexGestational Weight GainAdultAge FactorsDiabetes, GestationalFemaleHumansIncidenceMalaysiaOverweightPregnancyRetrospective StudiesRisk Factors

Identifiers

PMID32444832
PMCPMC7244566
OpenAlexW3027566164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.