Evidence map›Paper›PMID 32444502›Full record

ReviewHeart (British Cardiac Society)2020

Comprehensive review of evaluation and management of cardiac paragangliomas.

Sri Harsha Tella, Abhishek Jha, David Taïeb, Keith A Horvath, Karel Pacak

Open access · greenAbstract readReview
In one paragraph

Review in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiac Paraganglioma.JACC. Case reports · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. A Tumor-Feeding Artery Towards a Cardiac Glomus Tumor.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multimodality imaging of a cardiac paraganglioma: A case report.Frontiers in cardiovascular medicine · 2023
    Article
  19. Article
  20. Multimodality Imaging of Benign Primary Cardiac Tumor.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Sri Harsha TellaDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of South Carolina, Columbia, South Carolina, USA.
Abhishek JhaSection on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
David TaïebBiophysics and Nuclear Medicine, La Timone University Hospital, European Center for Research in Medical Imaging, Aix-Marseille University, Marseille, France.
Keith A HorvathClinical Transformation, Association of American Medical Colleges, Washington, District of Columbia, USA.
Karel PacakSection on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA karel@mail.nih.gov.ORCID 0000-0002-3541-3767
Aix-Marseille Université · FRAssociation of American Medical Colleges · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institutes of Health · USUniversity of South Carolina Upstate · US

Funding

Diagnosis, Pathophysiology And Molecular Biology of Pheochromocytoma and ParagangliomaZIAHD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2009 to 2024
$28.4M
Diagnosis &Pathophysiology of PheochromocytomaZ01HD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2001 to 2008
$1.7M
Intramural NIH HHS Z01 HD008735Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD008735
6 · The paper itself

Abstract

Cardiac paraganglioma (PGL) is a rare neuroendocrine tumour causing significant morbidity primarily due to norepinephrine secretion potentially causing severe hypertension, palpitations, lethal tachyarrhythmias, stroke and syncope. Cardiologists are faced with two clinical scenarios. The first is the elevated norepinephrine, whose actions must be properly counteracted by adrenoceptor blockade to avoid catastrophic consequences. The second is to evaluate the precise location of a cardiac PGL and its spread since compression of cardiovascular structures may result in ischaemia, angina, non-noradrenergic-induced arrhythmia, cardiac dysfunction or failure. Thus, appropriate assessment of elevated norepinephrine by its metabolite normetanephrine is a gold biochemical standard at present. Furthermore, dedicated cardiac CT, MRI and transthoracic echocardiogram are necessary for the precise anatomic information of cardiac PGL. Moreover, a cardiologist needs to be aware of advanced functional imaging using

Indexed as

Cardiac Imaging TechniquesCardiac Surgical ProceduresAdrenergic AntagonistsGenetic Predisposition to DiseaseHeart NeoplasmsHumansMultimodal ImagingParaganglioma, Extra-AdrenalPredictive Value of TestsRisk FactorsTreatment OutcomeAdrenergic Antagonistscardiac CT imagingcardiac imaging and diagnosticsgeneticspositron emission tomographic (PET) imagingsystemic review

Identifiers

PMID32444502
PMCPMC7482425
OpenAlexW3026056707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.