Evidence map›Paper›PMID 32444419›Full record

ArticleThe Journal of biological chemistry2020

How a tailor achieves the perfect fit.

Jeff D Colbert, Kenneth L Rock

Open access · hybridAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Spondyloarthritides: Theories and beyond.Frontiers in pediatrics · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeff D ColbertDepartment of Pathology, University of Massachusetts, Worcester, Massachusetts 01655.
Kenneth L RockDepartment of Pathology, University of Massachusetts, Worcester, Massachusetts 01655. Electronic address: Kenneth.Rock@umassmed.edu.
University of Massachusetts Chan Medical School · US

Funding

Role of Tspan5 in MHC I antigen presentation and cancer immune evasionR01AI114495 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROCK, KENNETH L · 2016 to 2025
$4.6M
Mechanisms of cross-presenting antigens in phagosomes on MHC I molecules to stimulate CD8 T lymphocyte responsesR01AI145932 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROCK, KENNETH L · 2019 to 2023
$2.1M
NIAID NIH HHS R01 AI114495NIAID NIH HHS R01 AI145932
6 · The paper itself

Abstract

Most antigenic peptides that bind stably to a major histocompatibility complex (MHC) I molecule for display to the immune system are approximately the same length, thanks in part to the expert trimming done by endoplasmic reticulum aminopeptidases (ERAPs), the final peptidases in the antigen-presentation pathway. An open question is whether ERAPs edit peptides to this optimal length while they are bound to MHC I molecules (using the latter as a pattern of sorts) or by free hand. Mavridis

Indexed as

Antigen PresentationHistocompatibility Antigens Class IAminopeptidasesEndoplasmic ReticulumMinor Histocompatibility AntigensPeptidesAminopeptidasesHistocompatibility Antigens Class IMinor Histocompatibility AntigensPeptides

Identifiers

PMID32444419
PMCPMC7247309
OpenAlexW3026116518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.