Evidence map›Paper›PMID 32443951›Full record

ReviewAnnual review of genomics and human genetics2020

Enhancer Predictions and Genome-Wide Regulatory Circuits.

Michael A Beer, Dustin Shigaki, Danwei Huangfu

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Reprogramming of neuronal genome function and phenotype by astrocytes.bioRxiv : the preprint server for biology · 2026
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  17. Host-pathogen protein-nucleic acid interactions: A comprehensive review.Computational and structural biotechnology journal · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael A BeerDepartment of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA; email: mbeer@jhu.edu.
Dustin ShigakiDepartment of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA; email: mbeer@jhu.edu.
Danwei HuangfuSloan Kettering Institute, New York, NY 10065, USA; email: huangfud@mskcc.org.
Johns Hopkins University · USKettering University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Understanding Pancreatic Progenitors for Diabetes Cell-Replacement TherapyR01DK096239 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI HUANGFU, DANWEI · 2012 to 2021
$4.4M
Systematic Identification of Core Regulatory Circuitry from ENCODE DataU01HG009380 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI BEER, MICHAEL A · 2017 to 2021
$2.6M
SVM-based Analysis of the Fine Scale Structure of Regulatory ElementsR01HG007348 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI BEER, MICHAEL A · 2013 to 2017
$2.3M
NCI NIH HHS P30 CA008748NHGRI NIH HHS R01 HG007348NHGRI NIH HHS U01 HG009380NIDDK NIH HHS R01 DK096239
6 · The paper itself

Abstract

Spatiotemporal control of gene expression during development requires orchestrated activities of numerous enhancers, which are

Indexed as

Enhancer Elements, GeneticGene Regulatory NetworksGenome, HumanComputational BiologyHumanscell fate switchingenhancersgene regulatory networksmachine learningsequence-based prediction

Identifiers

PMID32443951
PMCPMC7644210
OpenAlexW3027928376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.