Evidence map›Paper›PMID 32443922›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Detection and Diagnosis of Breast Cancer Using Artificial Intelligence Based assessment of Maximum Intensity Projection Dynamic Contrast-Enhanced Magnetic Resonance Images.

Mio Adachi, Tomoyuki Fujioka, Mio Mori, Kazunori Kubota, Yuka Kikuchi, Wu Xiaotong, Jun Oyama, Koichiro Kimura, Goshi Oda, Tsuyoshi Nakagawa and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Development of an Automated CAD System for Lesion Detection in DCE-MRI.Journal of imaging informatics in medicine · 2025
    Article
  7. Article
  8. The Evolution and Clinical Impact of Deep Learning Technologies in Breast MRI.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  9. Article
  10. Application of Machine Learning to Breast MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  11. Review
  12. Review
  13. AI Applications to Breast MRI: Today and Tomorrow.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  14. A Review of Artificial Intelligence in Breast Imaging.Tomography (Ann Arbor, Mich.) · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mio AdachiDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Tomoyuki FujiokaDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Mio MoriDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-6107-4519
Kazunori KubotaDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-3240-4910
Yuka KikuchiDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Wu XiaotongDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Jun OyamaDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Koichiro KimuraDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Goshi OdaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Tsuyoshi NakagawaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Hiroyuki UetakeDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Ukihide TateishiDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.

Funding

Japan Radiological Society Bayer Research Grant 2018 X2986
6 · The paper itself

Abstract

We aimed to evaluate an artificial intelligence (AI) system that can detect and diagnose lesions of maximum intensity projection (MIP) in dynamic contrast-enhanced (DCE) breast magnetic resonance imaging (MRI). We retrospectively gathered MIPs of DCE breast MRI for training and validation data from 30 and 7 normal individuals, 49 and 20 benign cases, and 135 and 45 malignant cases, respectively. Breast lesions were indicated with a bounding box and labeled as benign or malignant by a radiologist, while the AI system was trained to detect and calculate possibilities of malignancy using RetinaNet. The AI system was analyzed using test sets of 13 normal, 20 benign, and 52 malignant cases. Four human readers also scored these test data with and without the assistance of the AI system for the possibility of a malignancy in each breast. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were 0.926, 0.828, and 0.925 for the AI system; 0.847, 0.841, and 0.884 for human readers without AI; and 0.889, 0.823, and 0.899 for human readers with AI using a cutoff value of 2%, respectively. The AI system showed better diagnostic performance compared to the human readers (

Indexed as

artificial intelligencebreast imagingconvolutional neural networkdeep learningmagnetic resonance imagingobject detection

Identifiers

PMID32443922
PMCPMC7277981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.