Evidence map›Paper›PMID 32443652›Full record

ArticleMolecules (Basel, Switzerland)2020

Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.

Jong Min Oh, T M Rangarajan, Reeta Chaudhary, Rishi Pal Singh, Manjula Singh, Raj Pal Singh, Anna Rita Tondo, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. A Review of Biologically Active Oxime Ethers.Molecules (Basel, Switzerland) · 2023
    Review
  9. Chalcone: A Promising Bioactive Scaffold in Medicinal Chemistry.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Anticancer Activity of Natural and Synthetic Chalcones.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Jong Min OhDepartment of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea.
T M RangarajanDepartment of Chemistry, Sri Venketeswara College, University of Delhi, New Delhi-110021, India.ORCID 0000-0002-5972-1879
Reeta ChaudharyCentre for Fire, Explosive and Environment Saftey, DRDO, Delhi-110054, India.
Rishi Pal SinghDepartment of Chemistry, Sri Venketeswara College, University of Delhi, New Delhi-110021, India.
Manjula SinghDepartment of Chemistry, Shivaji College, University of Delhi, New Delhi-110027, India.
Raj Pal SinghCentre for Fire, Explosive and Environment Saftey, DRDO, Delhi-110054, India.
Anna Rita TondoDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari "Aldo Moro", via E. Orabona, 4, I-70125 Bari, Italy.
Nicola GambacortaDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari "Aldo Moro", via E. Orabona, 4, I-70125 Bari, Italy.
Orazio NicolottiDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari "Aldo Moro", via E. Orabona, 4, I-70125 Bari, Italy.
Bijo MathewDivision of Drug Design and Medicinal Chemistry Research Lab, Department of Pharmaceutical Chemistry, Ahalia School of Pharmacy, Palakkad-678557, Kerala, India.
Hoon KimDepartment of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea.ORCID 0000-0002-7203-3712
University of Delhi · INUniversity of Bari Aldo Moro · ITSunchon National University · KRCentre for Fire, Explosive and Environment Safety · INKerala School of Mathematics · IN

Funding

National Research Foundation of Korea (NRF) NRF-2019R1A2C1088967
6 · The paper itself

Abstract

Previously synthesized novel chalcone oxime ethers (COEs) were evaluated for inhibitory activities against monoamine oxidases (MAOs) and acetylcholinesterase (AChE). Twenty-two of the 24 COEs synthesized, except

Indexed as

AcetylcholinesteraseChalconeCholinesterase InhibitorsEthersHumansKineticsMonoamine OxidaseMonoamine Oxidase InhibitorsOximesAcetylcholinesteraseChalconeCholinesterase InhibitorsEthersMonoamine OxidaseMonoamine Oxidase InhibitorsOximesacetylcholinesterasechalconeskineticsmonoamine oxidaseoximesreversibility

Identifiers

PMID32443652
PMCPMC7288026
OpenAlexW3025581417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.