Evidence map›Paper›PMID 32443594›Full record

Trial reportCells2020

Blood Eosinophils Subtypes and Their Survivability in Asthma Patients.

Andrius Januskevicius, Egle Jurkeviciute, Ieva Janulaityte, Virginija Kalinauskaite-Zukauske, Skaidrius Miliauskas, Kestutis Malakauskas

2 registry-linked trialsOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05589779 unknown statusnot on this mapstarted 2023, after this paper: background citation

Relationship Between Cardiovascular Disease in Asthma and Eosinophil Subtypes and Biomarkers of Bronchial Remodeling.

TypeobservationalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2023 to 2024Enrolled40ConditionsAsthma, Cardiovascular DiseasesArmsAsthma and cardiovascular disease
NCT06911775 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Exploring Inflammatory and Regulatory Eosinophil Subpopulations: the Path to Precision Medicine for the Treatment of Eosinophilic-associated Diseases

TypeobservationalSponsorUniversity of FlorenceRan2025 to 2026Enrolled160ConditionsEosinophilic Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA), Hypereosinophilic Syndrome (HES)
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
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  3. Distinct miRNA expression patterns in circulating eosinophil subtypes and their subtype-derived exosomes in allergic asthma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrius JanuskeviciusLaboratory of Pulmonology, Department of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Egle JurkeviciuteLaboratory of Pulmonology, Department of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Ieva JanulaityteLaboratory of Pulmonology, Department of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Virginija Kalinauskaite-ZukauskeDepartment of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Skaidrius MiliauskasDepartment of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Kestutis MalakauskasLaboratory of Pulmonology, Department of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophils subtypes as lung-resident (rEOS) and inflammatory (iEOS) eosinophils are different in surface protein expression, functions, response to IL-5 and localization in lungs. rEOS- and iEOS-like eosinophils are found in blood; thus, we aimed to investigate their quantity and survivability in asthma patients. A total of 40 individuals were included: 10 steroid-free non-severe allergic asthma (AA), and 18 severe non-allergic eosinophilic asthma (SNEA) patients, the control group consisted of 12 healthy non-smoking subjects (HS). A bronchial challenge with

Indexed as

AdolescentAdultAnimalsAsthmaBronchial Provocation TestsCell AdhesionCell SurvivalDermatophagoides pteronyssinusEosinophilsFemaleHumansInflammationLungMaleMiddle AgedMyocytes, Smooth Muscleadhesionallergic asthmaeosinophils subtypesinflammatory eosinophilslung-resident eosinophilssevere eosinophilic asthmasurvivability

Identifiers

PMID32443594
PMCPMC7291159
OpenAlexW3025241684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.