Evidence map›Paper›PMID 32443586›Full record

ArticleGenes2020

Overcoming Immunological Challenges to Helper-Dependent Adenoviral Vector-Mediated Long-Term

Huibi Cao, Rongqi Duan, Jim Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Strategies for Modifying Adenoviral Vectors for Gene Therapy.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Huibi CaoProgram of Translational Medicine, The Hospital for Sick Children, Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Rongqi DuanProgram of Translational Medicine, The Hospital for Sick Children, Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Jim HuProgram of Translational Medicine, The Hospital for Sick Children, Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Hospital for Sick Children · CACanada Research Chairs · CA

Funding

CIHR MOP 125882
6 · The paper itself

Abstract

Cystic Fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (

Indexed as

Genetic TherapyAdenoviridaeAnimalsCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorGenetic VectorsGene Transfer TechniquesHumansImmunityLungMiceMiddle AgedCFTR protein, humanCftr protein, mouseCystic Fibrosis Transmembrane Conductance Regulatorcyclophosphamidecystic fibrosisgene therapytransient immunosuppression

Identifiers

PMID32443586
PMCPMC7291004
OpenAlexW3024467643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.