Evidence map›Paper›PMID 32443397›Full record

ArticleBiomolecules2020

Neurophysiological and Neurochemical Effects of the Putative Cognitive Enhancer (

Claudia Sagheddu, Nicholas Pintori, Predrag Kalaba, Vladimir Dragačević, Gessica Piras, Jana Lubec, Nicola Simola, Maria Antonietta De Luca, Gert Lubec, Marco Pistis

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  8. Review
  9. Neurogenetics and Epigenetics of Loneliness.Psychology research and behavior management · 2023
    Review
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  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Claudia SaghedduDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-5315-2898
Nicholas PintoriDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.
Predrag KalabaDepartment of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, 1010 Vienna, Austria.
Vladimir DragačevićDepartment of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, 1010 Vienna, Austria.
Gessica PirasDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.
Jana LubecDepartment of Neuroproteomics, Paracelsus Medical University, 5020 Salzburg, Austria.
Nicola SimolaDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.
Maria Antonietta De LucaDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-2647-4859
Gert LubecDepartment of Neuroproteomics, Paracelsus Medical University, 5020 Salzburg, Austria.
Marco PistisDepartment of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-4622-3205
University of Cagliari · ITParacelsus Medical University · ATUniversity of Vienna · AT

Funding

Regione Autonoma della Sardegna RASSR50209Università degli Studi di Cagliari PRID 2017
6 · The paper itself

Abstract

Treatments for cognitive impairments associated with neuropsychiatric disorders, such as attention deficit hyperactivity disorder or narcolepsy, aim at modulating extracellular dopamine levels in the brain. CE-123 (5-((benzhydrylsulfinyl)methyl) thiazole) is a novel modafinil analog with improved specificity and efficacy for dopamine transporter inhibition that improves cognitive and motivational processes in experimental animals. We studied the neuropharmacological and behavioral effects of the

Indexed as

CognitionAction PotentialsAnimalsBenzhydryl CompoundsDopamineDopamine AgentsDopamine Plasma Membrane Transport ProteinsDopaminergic NeuronsLimbic SystemMaleNootropic AgentsPrefrontal CortexPyramidal CellsRatsRats, Sprague-DawleyRewardBenzhydryl CompoundsCE-123DopamineDopamine AgentsDopamine Plasma Membrane Transport ProteinsNootropic Agentscognitive enhancerdopaminedopamine transportermodafinilprefrontal cortexpsychostimulantsreward

Identifiers

PMID32443397
PMCPMC7277835
OpenAlexW3025361970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.