Evidence map›Paper›PMID 32443376›Full record

ArticleMedicine2020

Effects of artemisinin on proliferation and apoptosis of human liver cancer HepG2 cells: A protocol of systematic review and meta-analysis.

Jing Li, Zhi-Ye Liu, Hai-Bo Yu, Qing Xue, Xiu-Sheng Qu

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Exploring the Chemopreventive Potential ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing LiDepartment of Physiology, Jiamusi University School of Basic Medical Sciences.
Zhi-Ye LiuDepartment of Chemotherapy and Radiotherapy, First Affiliated Hospital of Jiamusi University.
Hai-Bo YuDepartment of Cardiology, First Affiliated Hospital of Jiamusi University.
Qing XueClinical Medicine of Class 7 in Grade 2016, Jiamusi University, Jiamusi, 154002, China.
Xiu-Sheng QuDepartment of Chemotherapy and Radiotherapy, First Affiliated Hospital of Jiamusi University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study will examine the effects of artemisinin on proliferation and apoptosis of human liver cancer HepG2 cells (HLCHG-2C).

methodsThis study will systematically retrieve potential literatures in MEDLINE, Scopus, Web of Science, Cochrane Library, EMBASE, WANGFANG, and China National Knowledge Infrastructure from their initiation to the February 29, 2020. There are not limitations related to the language and publication time. All case-controlled studies (CCSs) or randomized controlled studies (RCSs) will be included in this study which investigated the effects of artemisinin on proliferation and apoptosis of HLCHG-2C. Two independent investigators will examine searched records, collect data from included studies, and will identify their methodological quality. Any divergences will be disentangled by discussion with another investigator. RevMan 5.3 software will be placed to pool the data and to carry out data analysis.

resultsThis study will summarize all eligible studies to test the effects of artemisinin on proliferation and apoptosis of HLCHG-2C.

conclusionThe results of this study will exert evidence to examine the effects of artemisinin on proliferation and apoptosis of HLCHG-2C, and it may benefit further research, patients, and healthcare providers. SYSTEMATIC REVIEW REGISTRATION: INPLASY202040075.

Indexed as

Anti-Infective AgentsApoptosisArtemisininsCell ProliferationHep G2 CellsHumansLiver NeoplasmsMeta-Analysis as TopicResearch DesignSystematic Reviews as TopicAnti-Infective AgentsartemisininArtemisinins

Identifiers

PMID32443376
PMCPMC7254480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.