Evidence map›Paper›PMID 32443368›Full record

ArticleMedicine2020

Association between microRNA 25 expression in serum and lung cancer: A protocol for systematic review and meta-analysis.

Peng Luo, Feng Qiao, Peng-Hui Dou, Shu-Min Li, Tian-Lu Zhang, Yu-Tong Xing, Gang Zhou, Su-Kun Xu, Jia-Bin Sun

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng LuoDepartment of Cardiothoracic Surgery.
Feng QiaoDepartment of Cardiothoracic Surgery.
Peng-Hui DouDepartment of Chemotherapy and Radiotherapy Department.
Shu-Min LiDepartment of Respiratory Medicine, First Affiliated Hospital of Jiamusi University, Jiamusi.
Tian-Lu ZhangDepartment of Cardiothoracic Surgery.
Yu-Tong XingDepartment of Cardiothoracic Surgery, Xiamen Fifth Hospital, Xiamen.
Gang ZhouDepartment of Cardiothoracic Surgery, Jiamusi Hongda Hospital.
Su-Kun XuDepartment of Chest Surgery, Jiamusi Tumor Hospital.
Jia-Bin SunDepartment of Critical Medicine, First Affiliated Hospital of Jiamusi University, Jiamusi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to identify the association between microRNA 25 (mRNA 25) expression in serum and lung cancer (LC).

methodsThis planned study will cover all eligible case-controlled studies that report association between mRNA 25 expression in serum and LC. It will include published studies from inception to the present in Cochrane Library, PUBMED, EMBASE, Web of Science, Allied and Complementary Medicine Database, VIP database, and China National Knowledge Infrastructure regardless language and geographical location. We will also search other sources, such as conference abstracts and reference lists of related known studies and experts in the domain consulted to avoid missing potential studies. Two contributors will independently examine and select studies, collect all necessary data, and judge study quality for all included studies. We will perform statistical analysis using RevMan V.5.3 software and Stata V.12.0 software.

resultsThis study will summarize current evidence to present first systematic review of research on the association between mRNA 25 expression in serum and LC.

conclusionThis study will present comprehensive evidence to determine whether mRNA 25 expression in serum is associated with LC, and will provide helpful evidence for the future studies. SYSTEMATIC REVIEW REGISTRATION: INPLASY202040056.

Indexed as

Biomarkers, TumorCase-Control StudiesEarly Detection of CancerHumansLung NeoplasmsMeta-Analysis as TopicMicroRNAsResearch DesignSystematic Reviews as TopicBiomarkers, TumorMicroRNAsMIRN25 microRNA, human

Identifiers

PMID32443368
PMCPMC7254826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.