Evidence map›Paper›PMID 32443327›Full record

ArticleMedicine2020

Clinicopathological significance of Ki67 expression in colorectal cancer: A protocol of systematic review and meta-analysis.

Jing Li, Zhi-Ye Liu, Hai-Bo Yu, Qing Xue, Wen-Jie He, Hai-Tao Yu

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jing LiDepartment of Physiology, Jiamusi University School of Basic Medical Sciences.
Zhi-Ye LiuDepartment of Chemotherapy and Radiotherapy.
Hai-Bo YuDepartment of Cardiology.
Qing XueClinical Medicine of Class 7 in Grade 2016, Jiamusi University.
Wen-Jie HeDepartment of Outpatient.
Hai-Tao YuDepartment of Anorect, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
Jiamusi University · CNS.P.E.C.I.E.S. · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study will investigate the diagnostic accuracy of Ki67 expression in colorectal cancer (CC).

methodsA comprehensive search in electronic bibliographic databases (MEDLINE, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure) will be performed from inception to the February 29, 2020 with no restrictions to the language and publication status. Two authors will examine the collected studies, extract essential data, and appraise study quality separately. If possible, we will estimate receiver operating characteristic (ROC), sensitivity and specificity by utilizing bivariate random effects and hierarchical summary ROC models.

resultsThis study will summarize present evidence to explore the diagnostic accuracy of Ki67 expression in CC.

conclusionThe findings of this study will clarify the diagnostic accuracy of Ki67 expression in CC. SYSTEMATIC REVIEW REGISTRATION: INPLASY202030009.

Indexed as

Biomarkers, TumorCase-Control StudiesColonic NeoplasmsColorectal NeoplasmsData AccuracyHumansKi-67 AntigenMeta-Analysis as TopicSensitivity and SpecificitySystematic Reviews as TopicBiomarkers, TumorKi-67 Antigen

Identifiers

PMID32443327
PMCPMC7253928
OpenAlexW3026557145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.