ArticleCurrent biology : CB2020
Object-Displacement-Sensitive Visual Neurons Drive Freezing in Drosophila.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Article
- Dynamic trajectory cues drive sequenced integration in approach detectors.bioRxiv : the preprint server for biology · 2026Article
- Robust Detection of Small Moving Objects Against Real-World Complex Dynamic Natural Environments: Drosophila-Inspired Visual Neural Pathway Modeling.Biomimetics (Basel, Switzerland) · 2026Article
- Spatial and morphological organization of mitochondria in neurons across a connectome.Science (New York, N.Y.) · 2026Article
- Combining visual motion and luminance features to enhance the detection of small moving objects in a bioinspired model.PLoS computational biology · 2026Article
- Visual circuitry for distance estimation in Drosophila.Current biology : CB · 2025Article
- Understanding the mechanism of facilitation in hoverfly TSDNs.PLoS computational biology · 2025Article
- On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025Review
- The visuomotor transformations underlying target-directed behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Morphological and functional convergence of visual projection neurons from diverse neurogenic origins in Drosophila.Nature communications · 2025Article
- Article
- Adaptation to visual sparsity enhances responses to isolated stimuli.Current biology : CB · 2024Article
- Article
- Social state gates vision using three circuit mechanisms inbioRxiv : the preprint server for biology · 2024Article
- Neural mechanisms to incorporate visual counterevidence in self-movement estimation.Current biology : CB · 2023Article
- Visual feedback neurons fine-tune Drosophila male courtship via GABA-mediated inhibition.Current biology : CB · 2023Article
- Neural mechanisms to incorporate visual counterevidence in self motion estimation.bioRxiv : the preprint server for biology · 2023Article
- Neural Circuit Mechanisms Involved in Animals' Detection of and Response to Visual Threats.Neuroscience bulletin · 2023Review
- Article
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Abstract
Visual systems are often equipped with neurons that detect small moving objects, which may represent prey, predators, or conspecifics. Although the processing properties of those neurons have been studied in diverse organisms, links between the proposed algorithms and animal behaviors or circuit mechanisms remain elusive. Here, we have investigated behavioral function, computational algorithm, and neurochemical mechanisms of an object-selective neuron, LC11, in Drosophila. With genetic silencing and optogenetic activation, we show that LC11 is necessary for a visual object-induced stopping behavior in walking flies, a form of short-term freezing, and its activity can promote stopping. We propose a new quantitative model for small object selectivity based on the physiology and anatomy of LC11 and its inputs. The model accurately reproduces LC11 responses by pooling fast-adapting, tightly size-tuned inputs. Direct visualization of neurotransmitter inputs to LC11 confirmed the model conjectures about upstream processing. Our results demonstrate how adaptation can enhance selectivity for behaviorally relevant, dynamic visual features.
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