Quantitation by liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry of DNA adducts derived from methyl glyoxal and carboxyethylating agents in leukocytes of smokers and non-smokers.
Guang Cheng, Sarah A Reisinger, Peter G Shields, Dorothy K Hatsukami, Silvia Balbo, Stephen S Hecht
Article in Chemico-biological interactions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors at 2 institutions in 1 country.
Guang ChengMasonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Sarah A ReisingerThe Ohio State University Comprehensive Cancer Center, Columbus, OH, 43210, USA.
Peter G ShieldsThe Ohio State University Comprehensive Cancer Center, Columbus, OH, 43210, USA.
Dorothy K HatsukamiMasonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Silvia BalboMasonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA. Electronic address: balbo006@umn.edu.
Stephen S HechtMasonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA. Electronic address: hecht002@umn.edu.
University of Minnesota Medical Center · USThe Ohio State University · US
Funding
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
Untargeted Adductomics to Characterize Ethnic Differences in the Exposome of SmokersP01CA138338 · NCI · UNIVERSITY OF MINNESOTA · PI STEPHEN S HECHT · 2010 to 2026
$33.4M
e-Cigarettes: Formaldehyde DNA Adducts, Oxidative Damage, and Potential Toxicity and CarcinogenesisR01CA203851 · NCI · UNIVERSITY OF MINNESOTA · PI HECHT, STEPHEN S · 2017 to 2021
A liquid chromatograpy-nanoelectrospray ionization-high resolution tandem mass spectrometry (LC-NSI-HRMS/MS) method was developed for quantitation of the DNA adducts 7-(2'-carboxyethyl)guanine (7-2'-CEG) and N
Indexed as
AdolescentAdultAgedAnimalsCattleChromatography, High Pressure LiquidDNADNA AdductsFemaleGuanineHumansLeukocytesMaleMiddle AgedNon-SmokersSmokers7-(2-carboxyethyl)guaninecalf thymus DNADNADNA AdductsGuanineN(2)-(1-carboxyethyl)guanine7-(2′-carboxyethyl)guanineAdvanced glycation end productsEndogenous nitrosationLiquid chromatograpy-nanoelectrospray ionization-high resolution tandem mass spectrometryMethyl glyoxalN(2)-(1′-carboxyethyl)guanine
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Quantitation by liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry of DNA adducts derived from methyl glyoxal and carboxyethylating agents in leukocytes of smokers and non-smokers. · full record | OpenQuestion