ArticleChemical senses2020
Relationship between odor intensity estimates and COVID-19 prevalence prediction in a Swedish population.
Article in Chemical senses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Regional and Chronological Variation of Chemosensory Dysfunction in COVID-19: a Meta-Analysis.Journal of Korean medical science · 2021Pooled it
- Prevalence of Chemosensory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis Reveals Significant Ethnic Differences.ACS chemical neuroscience · 2020Pooled it
- Quantitative but not qualitative flavor recognition impairments in COVID-19 patients.Irish journal of medical science · 2022Trial
- Olfactory training with Aromastics: olfactory and cognitive effects.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Trial
- Using SCENTinel® to predict SARS-CoV-2 infection: insights from a community sample during dominance of Delta and Omicron variants.Frontiers in public health · 2024Article
- Integrating the patient's voice into the research agenda for treatment of chemosensory disorders.Chemical senses · 2024Article
- Transient loss and recovery of oral chemesthesis, taste and smell with COVID-19: A small case-control series.Physiology & behavior · 2023Article
- Transient loss and recovery of oral chemesthesis, taste and smell with COVID-19: a small case-control series.medRxiv : the preprint server for health sciences · 2023Article
- Covid-19 affects taste independently of smell: results from a combined chemosensory home test and online survey from a global cohort (N=10,953).medRxiv : the preprint server for health sciences · 2023Article
- Covid-19 affects taste independent of taste-smell confusions: results from a combined chemosensory home test and online survey from a large global cohort.Chemical senses · 2023Article
- A quick test to objectify smell and taste dysfunction at home: a proof of concept for the validation of the chemosensory perception test.Chemical senses · 2023Article
- A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss.Rhinology · 2022Article
- Results from psychophysical tests of smell and taste during the course of SARS-CoV-2 infection: a review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022Review
- The COVOSMIA-19 trial: Preliminary application of the Singapore smell and taste test to objectively measure smell and taste function with COVID-19.Food quality and preference · 2022Article
- Varied Effects of COVID-19 Chemosensory Loss and Distortion on Appetite: Implications for Understanding Motives for Eating and Drinking.Foods (Basel, Switzerland) · 2022Article
- Retronasal olfactory testing in early diagnosed and suspected COVID-19 patients: a 7-week follow-up study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Loss of olfactory sensitivity is an early and reliable marker for COVID-19.Chemical senses · 2022Article
- An olfactory self-test effectively screens for COVID-19.Communications medicine · 2022Article
- Simple Disposable Odor Identification Tests for Predicting SARS-CoV-2 Positivity.International journal of environmental research and public health · 2021Article
- Acquired olfactory loss alters functional connectivity and morphology.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
In response to the COVID-19 pandemic, countries have implemented various strategies to reduce and slow the spread of the disease in the general population. For countries that have implemented restrictions on its population in a step-wise manner, monitoring of COVID-19 prevalence is of importance to guide decision on when to impose new, or when to abolish old, restrictions. We are here determining whether measures of odor intensity in a large sample can serve as one such measure. Online measures of how intense common household odors are perceived and symptoms of COVID-19 were collected from 2440 Swedes. Average odor intensity ratings were then compared to predicted COVID-19 population prevalence over time in the Swedish population and were found to closely track each other (r=-0.83). Moreover, we found that there was a large difference in rated intensity between individuals with and without COVID-19 symptoms and number of symptoms was related to odor intensity ratings. Finally, we found that individuals progressing from reporting no symptoms to subsequently reporting COVID-19 symptoms demonstrated a large drop in olfactory performance. These data suggest that measures of odor intensity, if obtained in a large and representative sample, can be used as an indicator of COVID-19 disease in the general population. Importantly, this simple measure could easily be implemented in countries without widespread access to COVID-19 testing or implemented as a fast early response before wide-spread testing can be facilitated.
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