Evidence map›Paper›PMID 32441549›Full record

ArticleVirulence2020

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis.

Catherine S Nation, Akram A Da'Dara, Patrick J Skelly

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Decrease of NADJournal of inflammation research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Schistosoma mansoni and the purinergic halo.Trends in parasitology · 2022
    Review
  8. Article
  9. Schistosome immunomodulators.PLoS pathogens · 2021
    Review
  10. Article
  11. Vitamin B6 Acquisition and Metabolism inFrontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Catherine S NationMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA, USA.ORCID 0000-0002-4197-3867
Akram A Da'DaraMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA, USA.
Patrick J SkellyMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA, USA.ORCID 0000-0002-5733-0524
Tufts University · US

Funding

Gene silencing in schistosomes using RNAiR01AI056273 · NIAID · TUFTS UNIVERSITY BOSTON · PI Patrick J Skelly · 2004 to 2026
$7.2M
Functional Characterization of the Schistosome TegumentR56AI056273 · NIAID · TUFTS UNIVERSITY BOSTON · PI SKELLY, PATRICK J · 2021 to 2021
$413k
NIAID NIH HHS HHSN272201000005CNIAID NIH HHS HHSN272201000005INIAID NIH HHS R01 AI056273NIAID NIH HHS R56 AI056273
6 · The paper itself

Abstract

Infection with intravascular platyhelminths of the genus

Indexed as

ApoptosisAnimalsFemaleHelminth ProteinsHydrolysisMiceMice, Inbred BALB CNADSchistosoma mansoniT-Lymphocytes, RegulatoryHelminth ProteinsNADimmunomodulationNADpurinergic signalingSchistosomaTregs

Identifiers

PMID32441549
PMCPMC7549896
OpenAlexW3026997233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.