Evidence map›Paper›PMID 32441527›Full record

ReviewChemical reviews2021

Antifungal Drug Resistance: Molecular Mechanisms in

Yunjin Lee, Emily Puumala, Nicole Robbins, Leah E Cowen

Open access · greenAbstract readReview
In one paragraph

Review in Chemical reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 411 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
411citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

411 citing papers in PubMed, 2 syntheses or guidelines pooled it, 735 citations in OpenAlex.

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  20. Modulating the amphiphilic character of porphyrins with pH-activatable cationic centers and fluorocarbon chains to enhance antimicrobial photodynamic activity against Candida albicans.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article

351 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yunjin LeeDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario M5G 1M1, Canada.
Emily PuumalaDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario M5G 1M1, Canada.
Nicole RobbinsDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario M5G 1M1, Canada.
Leah E CowenDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario M5G 1M1, Canada.ORCID 0000-0001-5797-0110
University of Toronto · CA

Funding

Systematic Analysis of Morphogenesis, Commensalism, and Virulence in a Leading Human Fungal PathogenR01AI127375 · NIAID · UNIVERSITY OF TORONTO · PI LEAH Elizabeth Cowen · 2017 to 2026
$5.3M
Targeting Hsp90 in cryptococcal fungal pathogenesisR01AI120958 · NIAID · UNIVERSITY OF TORONTO · PI BROWN, LAUREN ELAINE, COWEN, LEAH ELIZABETH · 2016 to 2019
$3.2M
CIHR FDN-154288NIAID NIH HHS R01 AI120958NIAID NIH HHS R01 AI127375
6 · The paper itself

Abstract

Fungal infections are a major contributor to infectious disease-related deaths across the globe.

Indexed as

AnimalsAntifungal AgentsCandidaCandida albicansCandida glabrataDrug DevelopmentDrug Resistance, FungalDrug Therapy, CombinationHumansMolecular StructureMycosesSignal TransductionVirulenceAntifungal Agents

Identifiers

PMID32441527
PMCPMC8519031
OpenAlexW3026958586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.