Evidence map›Paper›PMID 32441474›Full record

ArticleObesity (Silver Spring, Md.)2020

Impact of Combined Hormonal Contraceptive Use on Weight Loss: A Secondary Analysis of a Behavioral Weight-Loss Trial.

Ann E Caldwell, Adnin Zaman, Danielle M Ostendorf, Zhaoxing Pan, Bryan B Swanson, Suzanne Phelan, Holly R Wyatt, Daniel H Bessesen, Edward L Melanson, Victoria A Catenacci

Registry-linked trialAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05061472 (The Influence of Combined Oral Contraceptives on Weight, Body Composition, Eating Behaviors, and Appetite in Pre-menopausal Women With Overweight or Obesity), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05061472 completednot on this mapstarted 2022, after this paper: background citation

The Influence of Combined Oral Contraceptives on Weight, Body Composition, Eating Behaviors, and Appetite in Pre-menopausal Women With Overweight or Obesity

TypeobservationalSponsorUniversity of Colorado, DenverRan2022 to 2023Enrolled20ConditionsContraceptive Usage, Overweight or Obesity, Body Weight Changes, Appetitive Behavior
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ann E Caldwell *Anschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0001-9537-5216
Adnin Zaman *Anschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-6884-7748
Danielle M OstendorfAnschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-3923-5726
Zhaoxing PanDepartment of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Bryan B SwansonDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado, USA.
Suzanne PhelanKinesiology and Public Health Department, California Polytechnic State University, San Luis Obispo, California, USA.ORCID 0000-0003-2260-0499
Holly R WyattAnschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Daniel H BessesenAnschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Edward L MelansonDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Victoria A CatenacciAnschutz Health and Wellness Center, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0001-9723-3748

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Suppression of ERalpha in Hematopoietic Stem Cell-Derived Adipocytes Increases Adiposity via Kynurenine and the Aryl Hydrocarbon ReceptorU54AG062319 · NIA · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER · 2018 to 2026
$13.5M
Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss ProgramR01DK097266 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CATENACCI, VICTORIA A · 2013 to 2017
$3.1M
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
Rethinking Obesity and Cardiometabolic Health in Women: Using Evolutionarily Informed Hypotheses to Integrate Physiology and Behavior During Weight LossK01HL143039 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CALDWELL, ANN ELIZABETH · 2019 to 2023
$770k
NCATS NIH HHS UL1 TR002535NHLBI NIH HHS K01 HL143039NHLBI NIH HHS NIH T32HL116276NHLBI NIH HHS T32 HL116276NHLBI NIH HHS UL1TR002535NIA NIH HHS U54 AG062319NIDDK NIH HHS NIH R01 DK 097266NIDDK NIH HHS P30 DK 048520NIDDK NIH HHS P30 DK048520NIDDK NIH HHS P30 DK056336NIDDK NIH HHS R01 DK097266
6 · The paper itself

Abstract

objectiveThis study aimed to perform a preliminary investigation of the impact of combined hormonal contraceptive (CHC) use on weight loss during an 18-month behavioral weight-loss trial.

methodsAdults (n = 170; 18-55 years; BMI 27-42 kg/m

resultsAt 6 M, weight was reduced from baseline in both CHC (mean, -6.7 kg; 95% CI: -9.8 to -3.7 kg) and non-CHC (-9.1 kg; -9.1 to -6.4 kg). Between 6 and 18 M, CHC regained weight (4.9 kg; 0.9 to 8.9 kg), while weight remained relatively unchanged in non-CHC (-0.1 kg; -1.8 to 1.6 kg). At 18 M, weight was relatively unchanged from baseline in CHC (-1.8 kg; -7.3 to 3.6 kg) and was reduced from baseline in non-CHC (-7.9 kg; -10.2 to -5.5 kg).

conclusionsIn this secondary data analysis, CHC use was associated with weight regain after initial weight loss. Prospective studies are needed to further understand the extent to which CHC use influences weight loss and maintenance.

Indexed as

AdultContraceptive AgentsFemaleHumansMaleProspective StudiesWeight LossContraceptive Agents

Identifiers

PMID32441474
PMCPMC7556729

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.