Evidence map›Paper›PMID 32441459›Full record

ArticleEcology letters2020

Integrating data mining and transmission theory in the ecology of infectious diseases.

Barbara A Han, Suzanne M O'Regan, John Paul Schmidt, John M Drake

Abstract read
In one paragraph

Article in Ecology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  6. Review
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  11. Article
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  13. Live animal markets: Identifying the origins of emerging infectious diseases.Current opinion in environmental science & health · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Land-use change and rodent-borne diseases: hazards on the shared socioeconomic pathways.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  18. Predicting the zoonotic capacity of mammals to transmit SARS-CoV-2.bioRxiv : the preprint server for biology · 2021
    Article
  19. Impacts of biodiversity and biodiversity loss on zoonotic diseases.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Interventions can shift the thermal optimum for parasitic disease transmission.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Barbara A HanCary Institute of Ecosystem Studies, Box AB Millbrook, NY, 12571, USA.ORCID https://orcid.org/0000-0002-9948-3078
Suzanne M O'ReganDepartment of Mathematics and Statistics, North Carolina A&T State University, 1601 E. Market St., Greensboro, NC, 27411, USA.ORCID https://orcid.org/0000-0002-9446-955X
John Paul SchmidtOdum School of Ecology, University of Georgia, 140 E. Green St., Athens, GA, 30602, USA.ORCID https://orcid.org/0000-0001-8549-0587
John M DrakeOdum School of Ecology, University of Georgia, 140 E. Green St., Athens, GA, 30602, USA.ORCID https://orcid.org/0000-0003-4646-1235

Funding

Division of Environmental Biology 1717282NIMBioS
6 · The paper itself

Abstract

Our understanding of ecological processes is built on patterns inferred from data. Applying modern analytical tools such as machine learning to increasingly high dimensional data offers the potential to expand our perspectives on these processes, shedding new light on complex ecological phenomena such as pathogen transmission in wild populations. Here, we propose a novel approach that combines data mining with theoretical models of disease dynamics. Using rodents as an example, we incorporate statistical differences in the life history features of zoonotic reservoir hosts into pathogen transmission models, enabling us to bound the range of dynamical phenomena associated with hosts, based on their traits. We then test for associations between equilibrium prevalence, a key epidemiological metric and data on human outbreaks of rodent-borne zoonoses, identifying matches between empirical evidence and theoretical predictions of transmission dynamics. We show how this framework can be generalized to other systems through a rubric of disease models and parameters that can be derived from empirical data. By linking life history components directly to their effects on disease dynamics, our mining-modelling approach integrates machine learning and theoretical models to explore mechanisms in the macroecology of pathogen transmission and their consequences for spillover infection to humans.

Indexed as

RodentiaAnimalsData MiningDisease OutbreaksHumansModels, TheoreticalZoonosesBoosted regressiondisease dynamicsdisease macroecologypathogen transmissionrandom foreststatistical learningzoonosiszoonotic spillover

Identifiers

PMID32441459
PMCPMC7384120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.