Evidence map›Paper›PMID 32441287›Full record

ArticleLab on a chip2020

Remotely tunable microfluidic platform driven by nanomaterial-mediated on-demand photothermal pumping.

Guanglei Fu, Wan Zhou, XiuJun Li

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lab on a chip, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Guanglei FuDepartment of Chemistry and Biochemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu and Biomedical Engineering Research Center, Medical School of Ningbo University, Ningbo, Zhejiang 315211, P. R. China.ORCID 0000-0002-8128-1224
Wan ZhouDepartment of Chemistry and Biochemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu.ORCID 0000-0002-1439-9548
XiuJun LiDepartment of Chemistry and Biochemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu and Biomedical Engineering, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA and Border Biomedical Research Center, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA and Environmental Science and Engineering, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA.ORCID 0000-0002-7954-0717
The University of Texas at El Paso · USNingbo University · CN

Funding

Grafting DNA Codes on Paper for Rapid, Low-Cost, and Sensitive Meningitis DiagnosSC2GM105584 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI LI, XIUJUN · 2013 to 2015
$438k
Design of Point of Care Device for the Rapid Diagnosis of PertussisR21AI107415 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI DOMINGUEZ, DELFINA C, LI, XIUJUN · 2015 to 2016
$405k
NIAID NIH HHS R21 AI107415NIGMS NIH HHS SC2 GM105584
6 · The paper itself

Abstract

The requirement of on-demand microfluidic pumps and instrument-free readout methods remains a major challenge for the development of microfluidics. Herein, a new type of microfluidic platform, an on-demand photothermal microfluidic pumping platform, has been developed using an on-chip nanomaterial-mediated photothermal effect as novel and remotely tunable microfluidic driving force. The photothermal microfluidic pumping performance can be adjusted remotely by tuning the irradiation parameters, without changing on-chip parameters or replacing enzymes or other reagents. In contrast to graphene oxide, Prussian blue nanoparticles with higher photothermal conversion efficiency were used as the model photothermal agent to demonstrate the proof of concept. The on-chip pumping distance is linearly correlated with both the irradiation time and the nanomaterial concentration. The applications of photothermal microfluidic pumping have been demonstrated in multiplexed on-chip transport of substances, such as gold nanoparticles, and visual quantitative bar-chart detection of cancer biomarkers without using specialized instruments. Upon contact-free irradiation using a laser pointer, a strong on-chip nanomaterial-mediated photothermal effect can serve as a robust and remotely tunable microfluidic pump in a PMMA/PDMS hybrid bar-chart chip to drive ink bars in a visual quantitative readout fashion. This is the first report on a photothermal microfluidic pumping platform, which has great potential for various microfluidic applications.

Indexed as

Metal NanoparticlesNanostructuresGoldMicrofluidicsGold

Identifiers

PMID32441287
PMCPMC7384482
OpenAlexW3025332711

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.