Evidence map›Paper›PMID 32441199›Full record

ReviewOphthalmic genetics2020

Thales A C De Guimaraes, Michalis Georgiou, Anthony G Robson, Michel Michaelides

Abstract readReview
In one paragraph

Review in Ophthalmic genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Kv2.1/Kv8.2 Channels Regulate Fluid Homeostasis in the Outer Retina.bioRxiv : the preprint server for biology · 2026
    Article
  3. Bayesian Population-Based Prevalence Estimation ofInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Retinal Sensitivity Loss and Beyond inTurkish journal of ophthalmology · 2025
    Article
  7. Retinal Sensitivity in KCNV2-Associated Retinopathy.Investigative ophthalmology & visual science · 2025
    Article
  8. Novel and Previously Known Mutations of theJournal of clinical medicine · 2024
    Article
  9. Article
  10. The British journal of ophthalmology · 2024
    Article
  11. A versatile functional interaction between electrically silent KCellular and molecular life sciences : CMLS · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thales A C De GuimaraesUCL Institute of Ophthalmology, University College London , London, UK.ORCID 0000-0002-7936-6851
Michalis GeorgiouUCL Institute of Ophthalmology, University College London , London, UK.
Anthony G RobsonUCL Institute of Ophthalmology, University College London , London, UK.
Michel MichaelidesUCL Institute of Ophthalmology, University College London , London, UK.

Funding

Wellcome TrustWellcome Trust 099173/Z/12/Z
6 · The paper itself

Abstract

KCNV2: -associated retinopathy or "cone dystrophy with supernormal rod responses" is an autosomal recessive cone-rod dystrophy with pathognomonic ERG findings. This gene encodes Kv8.2, a voltage-gated potassium channel subunit that acts as a modulator by shifting the activation range of the K

Indexed as

MutationGenetic TherapyHumansPotassium Channels, Voltage-GatedRetinal DiseasesKCNV2 protein, humanPotassium Channels, Voltage-Gatedcone dystrophycone-rod dystrophyERGGene therapyKCNV2molecular geneticspotassium channelsretinal dystrophysupernormal rod responses

Identifiers

PMID32441199
PMCPMC7446039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.