Evidence map›Paper›PMID 32440989›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Evaluation of the diagnostic value of joint PET myocardial perfusion and metabolic imaging for vascular stenosis in patients with obstructive coronary artery disease.

Fanghu Wang, Weiping Xu, Wenbing Lv, Dongyang Du, Hui Feng, Xiaochun Zhang, Shuxia Wang, Wufan Chen, Lijun Lu

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Development and evaluation of a radiomics model of restingAnnals of translational medicine · 2022
    Article
  6. Article
  7. Value of combined perfusion and metabolic tracers versus stress-rest perfusion imaging for coronary heart disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fanghu Wang *School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China.
Weiping Xu *WeiLun PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, 106 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China.
Wenbing LvSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China.
Dongyang DuSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China.
Hui FengSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China.
Xiaochun ZhangWeiLun PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, 106 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China.
Shuxia WangWeiLun PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, 106 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China. wang_shuxia2002@aliyun.com.
Wufan ChenSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China. chenwufan_2016@gmail.com.
Lijun LuSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Road, Guangzhou, 510515, Guangdong, China. ljlubme@gmail.com.
Southern Medical University · CNGuangdong Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the diagnostic value of joint PET myocardial perfusion and metabolic imaging for vascular stenosis in patients with suspected obstructive coronary artery disease (CAD).

methodsEighty-eight patients (53 and 35 applied for training and validation, respectively) with suspected obstructive CAD were referred to

resultsIn univariate analysis, MIS outperformed other individual indicators in terms of sumScore (2.816-3.042 vs 2.138-2.908). In multivariate analysis, support vector machine (SVM) consisting of three indicators (MBF, SCR, and MIS) achieved the best performance (AUC 0.856, accuracy 0.810, sensitivity 0.838, specificity 0.757, and sumScore 3.261). This model consistently achieved significantly higher AUC compared with the SRS method for four specific subgroups (0.897, 0.839, 0.875, and 0.949 vs 0.775, 0.606, 0.713, and 0.744; P = 0.041, 0.005, 0.034 0.003, respectively).

conclusionsThe joint evaluation of PET rest MPI and MMI could improve the diagnostic performance for obstructive CAD. The multivariate model (MBF, SCR, and MIS) combined with SVM outperformed other methods.

Indexed as

Positron-Emission TomographyPositron Emission Tomography Computed TomographyAgedCoronary Artery DiseaseCoronary StenosisFemaleHumansMaleMiddle AgedMyocardial Perfusion ImagingRetrospective Studiescoronary artery diseasemachine learningmyocardial metabolic imagingMyocardial perfusion imaging

Identifiers

PMID32440989
OpenAlexW3027172793

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.