Evidence map›Paper›PMID 32440885›Full record

ArticleInternational urogynecology journal2021

Urinary symptoms and quality of life in women living with HIV: a cross-sectional study.

Maryse Larouche, Arianne Y K Albert, Nancy Lipsky, Sharon Walmsley, Mona Loutfy, Fiona Smaill, Sylvie Trottier, Ari Bitnun, Mark H Yudin, Geoffrey W Cundiff and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Geriatric syndromes in women living with HIV.Current opinion in HIV and AIDS · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maryse LaroucheDepartment of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada. ml.larouche@mcgill.ca.ORCID http://orcid.org/0000-0001-9942-5540
Arianne Y K AlbertWomen's Health Research Institute, Vancouver, BC, Canada.
Nancy LipskyWomen's Health Research Institute, Vancouver, BC, Canada.
Sharon WalmsleyDepartment of Infectious Diseases, Toronto General Hospital, Toronto, ON, Canada.
Mona LoutfyDepartment of Infectious Diseases, Women's College Hospital, Toronto, ON, Canada.
Fiona SmaillDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Sylvie TrottierDepartment of Microbiology, Infectious Diseases and Immunology, CHUQ/CHUL, Quebec, QC, Canada.
Ari BitnunDepartment of Infectious Diseases, SickKids, Toronto, ON, Canada.
Mark H YudinDepartment of Obstetrics and Gynecology & Reproductive Infectious Diseases, St. Michael's Hospital, Toronto, ON, Canada.
Geoffrey W CundiffDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.
Deborah M MoneyWomen's Health Research Institute, Vancouver, BC, Canada.

Funding

Canadian HIV Trials Network, Canadian Institutes of Health Research CTN 236CIHR MOP 136784
6 · The paper itself

Abstract

introduction and hypothesisTo determine prevalence and quality of life impact of lower urinary tract symptoms (LUTS) in women living with HIV (WLWH).

methodsCross-sectional urinary questionnaires were included in a multicenter national prospective study of the HPV vaccine in WLWH. Demographic and clinical information was abstracted from the parent study. The Urinary Distress Inventory (UDI-6) and Urinary Impact Questionnaire (UIQ-7) were administered. Wilcoxon rank sum, two-sample chi-square or Fisher's exact tests were used as appropriate to compare women with UDI-6 score ≥ 25 to those with lower UDI-6 scores on demographic and HIV-related factors. Significant categorical variables were followed up with logistic regression to estimate odds ratios (OR).

resultsOne hundred seventy-seven women completed urinary questionnaires (85.5% of cohort). Median age was 44.1 (37.2-50.6). Mean CD4 count was 621 (410-785), and 132 women (74.6%) were virologically suppressed. Median UDI-6 score was 4.2 (0-25). Fifty-one women (28.8%) had a UIQ-7 score > 0. Among those with a UDI-6 score of at least 25, median UIQ-7 was 9.5 (0-47.6). UDI-6 ≥ 25 was significantly associated with increasing age, higher BMI, Canada as country of origin, peri-/postmenopausal status (OR 3.37, 95% CI = 1.71 to 6.75) and being parous (OR 2.92, 95% CI = 1.27 to 7.59) (all p < 0.05). HIV-related factors were not associated with UDI-6 ≥ 25.

conclusionsLUTS were common, but we did not demonstrate a negative impact on quality of life in this sample of WLWH. Large comparative studies are needed to determine whether HIV is a risk factor for bothersome LUTS in women.

Indexed as

HIV InfectionsQuality of LifeAdultCanadaCross-Sectional StudiesFemaleHumansProspective StudiesSurveys and QuestionnairesHIVLower urinary tract symptoms (LUTS)Urinary incontinenceWomen living with HIV

Identifiers

PMID32440885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.