Evidence map›Paper›PMID 32440883›Full record

GuidelineJournal of thrombosis and thrombolysis2020

Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum.

Geoffrey D Barnes, Allison Burnett, Arthur Allen, Marilyn Blumenstein, Nathan P Clark, Adam Cuker, William E Dager, Steven B Deitelzweig, Stacy Ellsworth, David Garcia and 2 more

Open access · bronzeAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Journal of thrombosis and thrombolysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 252 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed, 16 pooled it
57.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

252 citing papers in PubMed, 16 syntheses or guidelines pooled it, 477 citations in OpenAlex.

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  11. Does Pulmonary Embolism in Critically Ill COVID-19 Patients Worsen the In-Hospital Mortality: A Meta-Analysis.Cardiovascular revascularization medicine : including molecular interventions · 2021
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  12. Active prescription of low-dose aspirin during or prior to hospitalization and mortality in COVID-19: A systematic review and meta-analysis of adjusted effect estimates.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 1 country.

Geoffrey D BarnesUniversity of Michigan, Ann Arbor, MI, 2800 Plymouth Rd, B14 G214, Ann Arbor, MI, 48109-2800, USA. gbarnes@med.umich.edu.
Allison BurnettUniversity of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Arthur AllenVA Salt Lake City Health Care System, Salt Lake City, UT, USA.
Marilyn BlumensteinChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Nathan P ClarkKaiser Permanente Colorado, Colorado University Skaggs School of Pharmacy, Aurora, CO, USA.
Adam CukerPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
William E DagerUC Davis Medical Center, Sacramento, CA, USA.
Steven B DeitelzweigOchsner Health System, New Orleans, LA, USA.
Stacy EllsworthHenry Ford Hospital, Detroit, MI, USA.
David GarciaUniversity of Washington, Seattle, WA, USA.
Scott KaatzHenry Ford Hospital, Detroit, MI, USA.
Tracy MinichielloUniversity of California, San Francisco, San Francisco VA Medical Center, San Francisco, CA, USA.
Henry Ford Hospital · USChildren's Hospital of Philadelphia · USOchsner Health System · USUniversity of California Davis Medical Center · USUniversity of California, San Francisco · USUniversity of Michigan · USUniversity of Montana · USUniversity of New Mexico · USUniversity of Pennsylvania · USUniversity of Washington · USVA Salt Lake City Healthcare System · US

Funding

Developing an Implementation Strategy to Improve Peri-procedural Anticoagulation Management for Patients with Atrial FibrillationK01HL135392 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARNES, GEOFFREY DOUGLAS · 2017 to 2021
$842k
NHLBI NIH HHS K01 HL135392
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a viral infection that can, in severe cases, result in cytokine storm, systemic inflammatory response and coagulopathy that is prognostic of poor outcomes. While some, but not all, laboratory findings appear similar to sepsis-associated disseminated intravascular coagulopathy (DIC), COVID-19- induced coagulopathy (CIC) appears to be more prothrombotic than hemorrhagic. It has been postulated that CIC may be an uncontrolled immunothrombotic response to COVID-19, and there is growing evidence of venous and arterial thromboembolic events in these critically ill patients. Clinicians around the globe are challenged with rapidly identifying reasonable diagnostic, monitoring and anticoagulant strategies to safely and effectively manage these patients. Thoughtful use of proven, evidence-based approaches must be carefully balanced with integration of rapidly emerging evidence and growing experience. The goal of this document is to provide guidance from the Anticoagulation Forum, a North American organization of anticoagulation providers, regarding use of anticoagulant therapies in patients with COVID-19. We discuss in-hospital and post-discharge venous thromboembolism (VTE) prevention, treatment of suspected but unconfirmed VTE, laboratory monitoring of COVID-19, associated anticoagulant therapies, and essential elements for optimized transitions of care specific to patients with COVID-19.

Indexed as

AnticoagulantsCoronavirus InfectionsCOVID-19HeparinHumansPandemicsPatient DischargePatient TransferPneumonia, ViralThrombolytic TherapyVenous ThromboembolismWarfarinAnticoagulantsHeparinWarfarinAnticoagulationCOVID-19Direct oral anticoagulantProphylaxisStewardshipVenous thromboembolism

Identifiers

PMID32440883
PMCPMC7241581
OpenAlexW3027329842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.