Evidence map›Paper›PMID 32440787›Full record

ReviewMedical microbiology and immunology2020

Tetraspanin CD53: an overlooked regulator of immune cell function.

V E Dunlock

Open access · hybridAbstract readReview
In one paragraph

Review in Medical microbiology and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 91 citations in OpenAlex.

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  12. Fast Variational Inference for Bayesian Factor Analysis in Single and Multi-Study Settings.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

V E DunlockDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Vera.Dunlock@radboudumc.nl.ORCID http://orcid.org/0000-0003-3149-7534
Radboud University Nijmegen · NL

Funding

European Research Council 724281
6 · The paper itself

Abstract

Tetraspanins are membrane organizing proteins that play a role in organizing the cell surface through the formation of subcellular domains consisting of tetraspanins and their partner proteins. These complexes are referred to as tetraspanin enriched microdomains (TEMs) or the tetraspanin web. The formation of TEMs allows for the regulation of a variety of cellular processes such as adhesion, migration, signaling, and cell fusion. Tetraspanin CD53 is a member of the tetraspanin superfamily expressed exclusively within the immune compartment. Amongst others, B cells, CD4

Indexed as

Cell AdhesionDendritic CellsGene Expression RegulationHumansLymphocytesMacrophagesMembrane MicrodomainsSignal TransductionTetraspanin 25CD53 protein, humanTetraspanin 25CD53Immune cell adhesionImmune cell signalingMembrane organizationTetraspanin enriched microdomainsTetraspanins

Identifiers

PMID32440787
PMCPMC7395052
OpenAlexW3028571758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.