Evidence map›Paper›PMID 32440601›Full record

ArticleChronic stress (Thousand Oaks, Calif.)

Hair Cortisol Concentration and Mental Disorder in Children With Chronic Physical Illness.

Emily Kornelsen, M Claire Buchan, Andrea Gonzalez, Mark A Ferro

Open access · goldAbstract read
In one paragraph

Article in Chronic stress (Thousand Oaks, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Cohort Profile: Multimorbidity in Children and Youth Across the Life-course (MY LIFE) Study.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emily KornelsenSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.
M Claire BuchanSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.
Andrea GonzalezDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Mark A FerroSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.ORCID https://orcid.org/0000-0002-0979-3233
University of Waterloo · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo examine changes in hair cortisol concentrations (HCC) in children with chronic physical illness and identify patterns of association between HCC and mental comorbidity.

methodsA sample of 50 children aged 6 to 16 years were recruited within six months of being diagnosed with a chronic physical illness. Data were collected via hair samples, structured interviews, and behavioral checklists.

resultsThere was no change in HCC over six months. Baseline HCC was associated with internalizing-odds ratio (OR) = 1.29 (90% confidence interval (CI): 1.01-1.66)-and externalizing disorders-OR = 1.32 (90% CI: 1.07-1.64). Externalizing disorder at six months was associated with elevated baseline-OR = 1.25 (90% CI: 1.02-1.53)-and six-month HCC-OR = 1.25 (90% CI: 1.02-1.54). Associations between HCC and mental disorder weakened over time, and for internalizing disorders, changed direction (i.e., inverse association), albeit not significantly.

conclusionResults provide preliminary evidence that physiological stress, measured using HCC, may be implicated in the relationship between physical and mental illness, and these associations align with attenuated stress responses over time.

Indexed as

adolescentchronic diseaseexternalizinginternalizingpsychiatric disorderstress

Identifiers

PMID32440601
PMCPMC7219865
OpenAlexW2973086031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.