Evidence map›Paper›PMID 32440587›Full record

ReviewChronic stress (Thousand Oaks, Calif.)

Default Mode Network Maturation and Environmental Adversities During Childhood.

Keila Rebello, Luciana M Moura, Walter H L Pinaya, Luis A Rohde, João R Sato

Open access · goldAbstract readReview
In one paragraph

Review in Chronic stress (Thousand Oaks, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Cortical Surface Area Profile Mediates Effects of Childhood Disadvantage on Later-Life General Cognitive Ability.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Childhood Disadvantage Moderates Late Midlife Default Mode Network Cortical Microstructure and Visual Memory Association.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Keila RebelloCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, Brazil.ORCID https://orcid.org/0000-0003-2980-8356
Luciana M MouraCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, Brazil.
Walter H L PinayaDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-3739-1087
Luis A RohdeDepartment of Psychiatry, Federal University of Rio Grande do Sul, Brazil.
João R SatoCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, Brazil.ORCID https://orcid.org/0000-0002-7503-9781
Universidade Federal do ABC · BRKing's College London · GBUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Default mode network (DMN) plays a central role in cognition and brain disorders. It has been shown that adverse environmental conditions impact neurodevelopment, but how these conditions impact in DMN maturation is still poorly understood. This article reviews representative neuroimaging functional studies addressing the interactions between DMN development and environmental factors, focusing on early life adversities, a critical period for brain changes. Studies focused on this period of life offer a special challenge: to disentangle the neurodevelopmental connectivity changes from those related to environmental conditions. We first summarized the literature on DMN maturation, providing an overview of both typical and atypical development patterns in childhood and early adolescence. Afterward, we focused on DMN changes associated with chronic exposure to environmental adversities during childhood. This summary suggests that changes in DMN development could be a potential allostatic neural feature associated with an embodiment of environmental circumstances. Finally, we discuss about some key methodological issues that should be considered in paradigms addressing environmental adversities and open questions for future investigations.

Indexed as

connectivitydefault mode networkenvironmental exposuretypical brain development

Identifiers

PMID32440587
PMCPMC7219900
OpenAlexW2901718855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.