Evidence map›Paper›PMID 32440479›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion.

Sander Bekeschus, Ramona Clemen, Felix Nießner, Sanjeev Kumar Sagwal, Eric Freund, Anke Schmidt

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 127 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Orchestration of Tumor-Associated Macrophages in the Tumor Cell-Macrophage-CD8International journal of biological sciences · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sander BekeschusZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.ORCID https://orcid.org/0000-0002-8773-8862
Ramona ClemenZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.
Felix NießnerZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.
Sanjeev Kumar SagwalZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.
Eric FreundZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.
Anke SchmidtZIK plasmatis Leibniz Institute for Plasma Science and Technology (INP Greifswald) Felix-Hausdorff-Str. 3 Greifswald 17489 Germany.
Leibniz Institute for Plasma Science and Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical technologies from physics are imperative in the diagnosis and therapy of many types of diseases. In 2013, a novel cold physical plasma treatment concept was accredited for clinical therapy. This gas plasma jet technology generates large amounts of different reactive oxygen and nitrogen species (ROS). Using a melanoma model, gas plasma technology is tested as a novel anticancer agent. Plasma technology derived ROS diminish tumor growth in vitro and in vivo. Varying the feed gas mixture modifies the composition of ROS. Conditions rich in atomic oxygen correlate with killing activity and elevate intratumoral immune-infiltrates of CD8

Indexed as

B16F10kINPenplasma medicinereactive nitrogen speciesreactive oxygen species

Identifiers

PMID32440479
PMCPMC7237847
OpenAlexW3013978766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.