Evidence map›Paper›PMID 32440262›Full record

ArticleAdvanced functional materials2018

Design, Fabrication, and Function of Silk-Based Nanomaterials.

Yu Wang, Jin Guo, Liang Zhou, Chao Ye, Fiorenzo G Omenetto, David L Kaplan, Shengjie Ling

Open access · greenAbstract read
In one paragraph

Article in Advanced functional materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 155 citations in OpenAlex.

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  12. Biomimetic Silk Architectures Outperform Animal Horns in Strength and Toughness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yu WangDepartment of Biomedical Engineering, Tufts University, MA 02155, USA.
Jin GuoDepartment of Biomedical Engineering, Tufts University, MA 02155, USA; Department of Chemical and Biological Engineering, Tufts University, MA 02155, USA.
Liang ZhouDepartment of Material Science and Engineering, AnHui Agricultural University, Hefei 230036, China.
Chao YeSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Fiorenzo G OmenettoDepartment of Biomedical Engineering, Tufts University, MA 02155, USA.
David L KaplanDepartment of Biomedical Engineering, Tufts University, MA 02155, USA.
Shengjie LingSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Tufts University · USShanghaiTech University · CNAnhui Agricultural University · CN

Funding

Craniofacial Tissue EngineeringR01DE016525 · NIDCR · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2005 to 2017
$5.5M
Models to Predict Protein Biomaterial PerformanceU01EB014976 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BUEHLER, MARKUS J., KAPLAN, DAVID L. · 2012 to 2020
$5.2M
Degradable orthopedic hardwareR01AR068048 · NIAMS · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L., LIN, SAMUEL J · 2015 to 2020
$2.0M
NIAMS NIH HHS R01 AR068048NIBIB NIH HHS U01 EB014976NIDCR NIH HHS R01 DE016525
6 · The paper itself

Abstract

Animal silks are built from pure protein components and their mechanical performance, such as strength and toughness, often exceed most engineered materials. The secret to this success is their unique nanoarchitectures that are formed through the hierarchical self-assembly of silk proteins. This natural material fabrication process in sharp contrast to the production of artificial silk materials, which usually are directly constructed as bulk structures from silk fibroin (SF) molecular. In recent years, with the aim of understanding and building better silk materials, a variety of fabrication strategies have been designed to control nanostructures of silks or to create functional materials from silk nanoscale building blocks. These emerging fabrication strategies offer an opportunity to tailor the structure of SF at the nanoscale and provide a promising route to produce structurally and functionally optimized silk nanomaterials. Here, we review the critical roles of silk nanoarchitectures on property and function of natural silk fibers, outline the strategies of utilization of these silk nanobuilding blocks, and we provide a critical summary of state of the art in the field to create silk nanoarchitectures and to generate silk-based nanocomponents. Further, such insights suggest templates to consider for other materials systems.

Indexed as

biomineralizationcarbon nanomaterialsnanofabricationnanomaterialssilk

Identifiers

PMID32440262
PMCPMC7241600
OpenAlexW2900498299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.