Evidence map›Paper›PMID 32440119›Full record

ArticleInternational journal of nanomedicine2020

Synthesis and Characterization of Fluoridated Silver Nanoparticles and Their Potential as a Non-Staining Anti-Caries Agent.

Iris Xiaoxue Yin, Irene Shuping Zhao, May Lei Mei, Edward Chin Man Lo, Jinyao Tang, Quanli Li, Lok Yan So, Chun Hung Chu

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Silver Compounds for Caries Management.International dental journal · 2024
    Review
  14. Copper Materials for Caries Management: A Scoping Review.Journal of functional biomaterials · 2023
    Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iris Xiaoxue YinFaculty of Dentistry, The University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0003-1167-2999
Irene Shuping ZhaoSchool of Dentistry, Shenzhen University Health Science Center, Shenzhen, People's Republic of China.ORCID 0000-0002-0572-2753
May Lei MeiFaculty of Dentistry, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-2663-4576
Edward Chin Man LoFaculty of Dentistry, The University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0002-3618-0619
Jinyao TangDepartment of Chemistry, The University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0002-0051-148X
Quanli LiSchool of Stomatology, Anhui Medical University, Hefei, People's Republic of China.
Lok Yan SoDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, People's Republic of China.
Chun Hung ChuFaculty of Dentistry, The University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0002-8167-0430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe first objective of this study was to prepare sodium fluoride (NaF) solution with various concentrations of polyethylene glycol-coated silver nanoparticles (PEG-AgNPs). The second objective was to study the antibacterial activity against

methodsPEG-AgNPs were prepared via the one-step chemical reduction of silver acetate with thiolated polyethylene glycol. The PEG-AgNPs were characterized with ultraviolet-visible spectrometry and transmission electron microscopy. The half maximal inhibitory concentration (IC50) for the PEG-AgNPs against

resultsThe PEG-AgNPs have an average diameter of 2.56±0.43 nm and showed excellent stability at high ionic strength (2.5% NaF) for 18 months. The IC50 of PEG-AgNPs against

conclusionA biocompatible solution of NaF with PEG-AgNPs was developed. Because it has antibacterial activity against

Indexed as

Staining and LabelingAnti-Bacterial AgentsCariostatic AgentsDental CariesFluoridesGingivaHumansMetal NanoparticlesMicrobial Sensitivity TestsPolyethylene GlycolsSilverSpectrophotometry, UltravioletStreptococcus mutansAnti-Bacterial AgentsCariostatic AgentsFluoridesPolyethylene GlycolsSilverantibacterialcariesdentinfluoridenanoparticlessilver

Identifiers

PMID32440119
PMCPMC7212993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.