Evidence map›Paper›PMID 32439940›Full record

ArticleScientific reports2020

Egg oil from Portunus trituberculatus alleviated obesity and regulated gut microbiota in mice.

Shiwei Hu, Huicheng Yang, Xiang Gao, Shijie Li, Wei Jiang, Yu Liu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Nutrients · 2025
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  2. Translational animal science · 2024
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  6. Phosphatidylserine fromMarine drugs · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shiwei HuInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhoushan, 316022, China. hushiweihai@163.com.
Huicheng YangZhejiang Marine Development Research Institute, Zhoushan, 316021, China. huichengy@163.com.
Xiang GaoCollege of Food Science, Qingdao University, Qingdao, 266071, China.
Shijie LiInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhoushan, 316022, China.
Wei JiangInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhoushan, 316022, China.
Yu LiuInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhoushan, 316022, China.
Zhejiang Ocean University · CNQingdao University · CNZhejiang Marine Fisheries Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Egg oil from Portunus trituberculatus (Pt-egg oil) can overcome insulin resistance resulting from abundant bioactive lipids. However, its effects on obesity and gut microbiota were unclear. Here, we evaluated whether Pt-egg oil could improve obesity and gut microbiota or not in high-fat diet feeding mice. Results exhibited that Pt-egg oil markedly reduced body weight and adipose weight gain, improved lipid accumulation and circulatory cytokines, inhibited epididymal adipose cell size. Moreover, Pt-egg oil modified gut microbiota, involving decreases in the ratio of Firmicutes to Bacteroidetes, Proteobacteria, Actinobacteria, and increase in Verrucomicrobia phylum. Pt-egg oil reduced serum and fecal lipopolysaccharide (LPS) levels and down-regulated Toll-like receptor 4 pathway in both epididymal adipose and liver tissues. Meanwhile, Pt-egg oil increased short chain fatty acids and up-regulated of G-protein-coupled receptors in both epididymal adipose and liver tissues. These suggest that Pt-egg oil could be alternative food supplement for the prophylactic effects on anti-obesity and improvement in human gut health.

Indexed as

Insulin ResistanceAnimalsBlood GlucoseBrachyuraDietary SupplementsDiet, High-FatGastrointestinal MicrobiomeMaleMiceMice, Inbred C57BLObesityOilsBlood Glucoseegg-oilOils

Identifiers

PMID32439940
PMCPMC7242455
OpenAlexW3027942511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.