Evidence map›Paper›PMID 32439753›Full record

ArticleImmunoHorizons2020

Expression Efficiency of Multiple

Rakshin Kharwadkar, Benjamin J Ulrich, Amina Abdul Qayum, Byunghee Koh, Paula Licona-Limón, Richard A Flavell, Mark H Kaplan

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rakshin KharwadkarHerman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.ORCID 0000-0002-6303-1651
Benjamin J UlrichHerman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Amina Abdul QayumHerman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Byunghee KohHerman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Paula Licona-LimónDepartamento de Biologia Celular y del Desarrollo, Instituto de Fisiologia Celular, Universidad Nacional Autónoma de México, 04020 Mexico City, Mexico; and.
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0003-4461-0778
Mark H KaplanHerman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202; mkaplan2@iupui.edu.ORCID 0000-0002-2923-8245
Indiana University – Purdue University Indianapolis · USUniversidad Nacional Autónoma de México · MXYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Sara K Quinney · 1999 to 2026
$59.3M
Project-005U54DK106846 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Reuben Kapur, Karen Elizabeth Pollok · 2015 to 2026
$9.7M
The role of PU.1 in T helper cell heterogeneityR01AI057459 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI KAPLAN, MARK H · 2005 to 2025
$8.2M
REGULATION OF HEMATOPOIETIC CELL PRODUCTIONT32DK007519 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI KAPLAN, MARK H · 1986 to 2020
$7.1M
Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Th9 cells in immediate hypersensitivityR01AI129241 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2017 to 2021
$2.0M
Identification of regulatory elements in the Il9 geneR03AI135356 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2018 to 2019
$158k
IL-9-secreting tissue-resident memory T cells in allergic airway diseaseF30HL147515 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI ULRICH, BENJAMIN · 2019 to 2019
$30k
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA082709NHLBI NIH HHS F30 HL147515NIAID NIH HHS R01 AI057459NIAID NIH HHS R01 AI129241NIAID NIH HHS R03 AI135356NIAID NIH HHS T32 AI060519NIDDK NIH HHS T32 DK007519NIDDK NIH HHS U54 DK106846
6 · The paper itself

Abstract

Generation of allelic gene reporter mice has provided a powerful tool to study gene function in vivo. In conjunction with imaging technologies, reporter mouse models facilitate studies of cell lineage tracing, live cell imaging, and gene expression in the context of diseases. Although there are several advantages to using reporter mice, caution is important to ensure the fidelity of the reporter protein representing the gene of interest. In this study, we compared the efficiency of two

Indexed as

AllelesCell LineageAnimalsCell DifferentiationChromatin ImmunoprecipitationFluorescent Antibody TechniqueImmunity, InnateMiceMice, 129 StrainMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutReceptors, Interleukin-9T-Lymphocytes, Helper-InducerIl9r protein, mouseReceptors, Interleukin-9

Identifiers

PMID32439753
PMCPMC7678022
OpenAlexW3026318497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.