Evidence map›Paper›PMID 32439489›Full record

ArticlePreventive medicine2020

Symptoms of depression and active smoking among survivors of stroke and myocardial infarction: An NHANES analysis.

Neal S Parikh, Setareh Salehi Omran, Hooman Kamel, Mitchell S V Elkind, Joshua Willey

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Depression, health anxiety, and five-year mortality after ST-elevation myocardial infarction: the SEMI-CI cohort.International journal of cardiology. Cardiovascular risk and prevention · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Neal S ParikhClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, 420 E 70th St, 4th floor, New York, NY 10021, USA. Electronic address: nsp2001@med.cornell.edu.
Setareh Salehi OmranDepartment of Neurology, University of Colorado, 12401 E 17th Ave, Leprino Building, 4th floor, Aurora, CO 80045, USA.
Hooman KamelClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, 420 E 70th St, 4th floor, New York, NY 10021, USA.
Mitchell S V ElkindDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, 710 W 168th St, 6th floor, New York, NY 10032, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, 710 W 168th St, 6th floor, New York, NY 10032, USA.
Joshua WilleyDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, 710 W 168th St, 6th floor, New York, NY 10032, USA.
Columbia University · USCornell University · USUniversity of Colorado Denver · USWeill Cornell Medicine · US

Funding

NEUROEPIDEMIOLOGY TRAINING PROGRAMT32NS007153 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GU, YIAN, WILLEY, JOSHUA ZEBADIAH · 1987 to 2023
$6.2M
Stroke Trials Network of Columbia and CornellU24NS107237 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDWARD SANDER CONNOLLY, Randolph S Marshall · 2018 to 2026
$3.1M
NINDS NIH HHS T32 NS007153NINDS NIH HHS U24 NS107237
6 · The paper itself

Abstract

Historic concerns about the cardiovascular and neuropsychiatric side effects of smoking-cessation pharmacotherapy have in part limited their use. We sought to evaluate whether depressive symptoms are associated with active smoking among survivors of stroke and myocardial infarction (MI). To do this, we performed a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (2005-2016). We included participants ≥20 years old with prior stroke or MI and any history of smoking. Symptoms of depression, at survey participation, were ascertained using the Patient Health Questionnaire-9. Active smoking was defined using self-report and, secondarily, with cotinine measures. We used logistic regression to evaluate the association between depression and active smoking after adjusting for demographics, smoking-related medical conditions, and health-related behaviors. We found that, among stroke and MI survivors with any history of smoking, 37.9% (95% CI, 34.5-41.3%) reported active smoking and 43.8% (95% CI, 40.3-47.3%) had biochemical evidence of smoking. Rates of active smoking were similar for stroke and MI survivors. Twenty-one percent screened positive for depression. In adjusted models, depression was associated with active smoking in the combined group of stroke and MI survivors (odds ratio, 2.28; 95% CI, 1.24-4.20) and in stroke survivors (odds ratio, 2.97; 95% CI, 1.20-7.38). Tests of heterogeneity by event type did not reveal an interaction. Findings were similar when using cotinine measures. We conclude that symptoms of depression were associated with active smoking among stroke and MI survivors. Stroke and MI survivors with symptoms of depression may require targeted smoking-cessation interventions.

Indexed as

DepressionMyocardial InfarctionSmokingStrokeSurvivorsAdultAgedCross-Sectional StudiesFemaleHumansMaleMedicareNutrition SurveysRisk FactorsUnited StatesYoung AdultCerebrovascular disease/strokeDepressionEpidemiologyMyocardial infarctionRisk factorsSecondary preventionSmoking

Identifiers

PMID32439489
PMCPMC7309407
OpenAlexW3026113646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.