Evidence map›Paper›PMID 32438905›Full record

Trial reportBMC musculoskeletal disorders2020

Thigh musculature stiffness during active muscle contraction after anterior cruciate ligament injury.

April L McPherson, Nathaniel A Bates, Clifton R Haider, Takashi Nagai, Timothy E Hewett, Nathan D Schilaty

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

April L McPhersonMayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA.
Nathaniel A BatesDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Clifton R HaiderSpecial Purpose Processor Development Group, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Takashi NagaiDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Timothy E HewettSparta Science, Menlo Park, CA, USA.
Nathan D SchilatyDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. Schilaty.nathan@mayo.edu.ORCID http://orcid.org/0000-0002-6038-7126
Mayo Clinic · USMayo Clinic in Arizona · USMayo Clinic in Florida · USMenlo School · US

Funding

Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female AthletesR01AR055563 · NIAMS · OHIO STATE UNIVERSITY · PI BATES, NATHANIEL ANDREW, KRYCH, AARON · 2008 to 2022
$5.9M
Multi-faceted Approach to Modeling ACL Injury MechanismsR01AR056259 · NIAMS · OHIO STATE UNIVERSITY · PI HEWETT, TIMOTHY E · 2009 to 2017
$4.9M
NIAMS NIH HHS L30 AR070273NIAMS NIH HHS R01 AR055563NIAMS NIH HHS R01 AR056259NICHD NIH HHS K12 HD065987NIH HHS K12HD065987NIH HHS L30AR070273NIH HHS R01AR056259
6 · The paper itself

Abstract

backgroundAltered motor unit (MU) activity has been identified after anterior cruciate ligament (ACL) injury, but its effect on muscle tissue properties is unknown. The purpose of this study was to compare thigh musculature muscle stiffness between control and ACL-injured subjects.

methodsThirty ACL-injured subjects and 25 control subjects were recruited. Subjects completed a randomized protocol of isometric contractions while electromyography (EMG) signals were recorded. Three maximum voluntary isometric contractions (MVIC) determined peak force for 10 and 25% MVIC trials. Shear wave elastography was captured during each 10 and 25% MVIC trials.

resultsDifferences in muscle stiffness were assessed between limbs and groups. 12 months post-surgery had higher stiffness for VM 0% MVIC, VL 0 and 10% MVIC, and ST 10 and 25% MVIC (all p ≤ 0.04).

conclusionThigh musculature stiffness changed throughout rehabilitation and remained altered at 12 months after ACL reconstruction.

Indexed as

AdolescentAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionElectromyographyFemaleHumansIsometric ContractionLinear ModelsMaleMuscle ContractionMuscle StrengthThighYoung AdultACL reconstructionArthrogenic muscle inhibitionEMG decompositionRehabilitationShear wave elastography

Identifiers

PMID32438905
PMCPMC7243327
OpenAlexW3027437928

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.