Evidence map›Paper›PMID 32438747›Full record

ArticleJournal of clinical medicine2020

Academia Europaea Position Paper on Translational Medicine: The Cycle Model for Translating Scientific Results into Community Benefits.

Péter Hegyi, Ole H Petersen, Stephen Holgate, Bálint Erőss, András Garami, Zsolt Szakács, Dalma Dobszai, Márta Balaskó, Lajos Kemény, Shuang Peng and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 67 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 67 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 67 syntheses or guidelines pooled it.

  1. Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  2. Large-scale meta-analysis of infection risk with JAK-STAT inhibitors in 29,000 patients.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
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85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Péter HegyiInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Ole H PetersenSchool of Biosciences, Cardiff University, Cardiff CF10 3AX, Wales, UK.
Stephen HolgateClinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.
Bálint ErőssInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
András GaramiInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Zsolt SzakácsInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Dalma DobszaiInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Márta BalaskóInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Lajos KeményDepartment of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.
Shuang PengDepartment of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510632, China.
Joao MonteiroNature Medicine, New York, NY 10004-1562, USA.
András VarróDepartment of Pharmacology and Pharmacotherapy, University of Szeged, 6720 Szeged, Hungary.
Tara LamontNIHR Dissemination Centre, University of Southampton, Southampton SO16 7NS, UK.
Jeffrey LaurenceWeill Cornell Medical College, New York, NY 10065, USA.
Zoe GrayNational Institute for Health Research, Southampton SO16 7NS, UK.
Andrew PicklesBiostatistics and Health Informatics, King's College London, London WC2R 2LS, UK.
Garret A FitzGeraldInstitute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Christopher E M GriffithsDermatology Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester M13 9WU, UK.
Jacek JassemMedical University of Gdańsk, 80-210 Gdańsk, Poland.
Dmitri A RusakovUCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Alexei VerkhratskyFaculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
Andrea SzentesiInstitute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.

Funding

Economic Development and Innovation Operational Programme Grant GINOP 2.3.2-15-2016-00048Hubert Curien Initiatives Fund of Academia Europaea via its Cardiff Knowledge Hub -Maudsley NHS Foundation Trust -Medical School of the University of Pécs -Medical Scientific Research Foundation of Guangdong Province, China A2019205National Institute of Health U54TR001623NIHR Biomedical Research Centre at South London -NIHR Manchester Biomedical Research Centre -NIHR Senior Investigator award NF-SI-0617-10120
6 · The paper itself

Abstract

introductionTranslational science has gained prominence in medicine, but there is still much work to be done before scientific results are used optimally and incorporated into everyday health practice. As the main focus is still on generating new scientific data with financial resources primarily available for that purpose, other activities that are necessary in the transition from research to community benefit are considered less needy. The European Statistical Office of the European Commission has recently reported that 1.7 million people under 75 years of age died in Europe in 2016, with around 1.2 million of those deaths being avoidable through effective primary prevention and public health intervention. Therefore, Academia Europaea, one of the five Pan-European networks that form SAPEA (Science Advice for Policy by European Academies), a key element of the European Commission's Scientific Advice Mechanism (SAM), has launched a project to develop a model to facilitate and accelerate the utilisation of scientific knowledge for public and community benefit.

methodsDuring the process, leaders in the field, including prominent basic and clinical researchers, editors-in-chief of high-impact journals publishing translational research articles, translational medicine (TM) centre leaders, media representatives, academics and university leaders, developed the TM cycle, a new model that we believe could significantly advance the development of TM.

resultsThis model focuses equally on the acquisition of new scientific results healthcare, understandable and digestible summation of results, and their communication to all participants. We have also renewed the definition in TM, identified challenges and recommended solutions.

conclusionThe authors, including senior officers of Academia Europaea, produced this document to serve as a basis for revising thinking on TM with the end result of enabling more efficient and cost-effective healthcare.

Indexed as

communicationhealthcareinterdisciplinaryknowledgesciencetranslationtranslational medicine

Identifiers

PMID32438747
PMCPMC7290380

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.