ReviewAnimals : an open access journal from MDPI2020
A Review of the Effect of Formic Acid and Its Salts on the Gastrointestinal Microbiota and Performance of Pigs.
Review in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 78 citations in OpenAlex.
- Probiotic Therapy of Gastrointestinal Symptoms During COVID-19 Infection: A Randomized, Double-Blind, Placebo-Controlled, Remote Study.Nutrients · 2024Trial
- Dietary potassium diformate improves slaughter performance, systemic metabolic homeostasis, and intestinal health without compromising growth performance in Qingyuan Partridge chickens.Poultry science · 2026Article
- Dietary supplementation with microencapsulated organic acids and essential oils improves sow productivity and nursery pig performance under commercial field conditions.Porcine health management · 2026Article
- Potential Antidiabetic Inhibitors and Antimicrobials from the FungusJournal of microbiology and biotechnology · 2025Article
- Genomic and phenotypic insights into broad-spectrum antiVeterinary world · 2025Article
- Effects of Dietary Potassium Diformate Supplementation on Growth Performance, Nutrient Digestibility, Gastrointestinal pH, Jejunal Morphology, Digestive Enzyme Activity, and Antioxidant Status in Weaned Piglets.Animals : an open access journal from MDPI · 2025Article
- Effects of paraformic acid supplementation, as an antibiotic replacement, on growth performance, intestinal morphology and gut microbiota of nursery pigs.Journal of animal science and technology · 2025Article
- Gut microbiota in multiple sclerosis and animal models.The FEBS journal · 2025Review
- Characterization of Functional Properties and Organic Acids inInternational journal of food science · 2025Article
- Dietary supplementation with a novel acidifier sodium diformate improves growth performance by increasing growth-related hormones levels and preventsFrontiers in veterinary science · 2024Article
- Polycaprolactone/Anthocyanin-Based Electrospun Volatile Amines Gas Indicator with Improved Visibility by Varying Bi-Solvent Ratio: A Case of Intelligent Packaging of Mackerel.Foods (Basel, Switzerland) · 2023Article
- Article
- U mobilization and associated U isotope fractionation by sulfur-oxidizing bacteria.Frontiers in microbiology · 2023Article
- Supplementation of Paraformic Acid as a Substitute for Antibiotics in the Diet Improves Growth Performance and Liver Health in Broiler Chickens.Animals : an open access journal from MDPI · 2022Article
- Acidifiers Attenuate Diquat-Induced Oxidative Stress and Inflammatory Responses by Regulating NF-κB/MAPK/COX-2 Pathways in IPEC-J2 Cells.Antioxidants (Basel, Switzerland) · 2022Article
- Effects of formic acid and glycerol monolaurate on weanling pig growth performance, fecal consistency, fecal microbiota, and serum immunity.Translational animal science · 2022Article
- Review on Preventive Measures to Reduce Post-Weaning Diarrhoea in Piglets.Animals : an open access journal from MDPI · 2022Review
- The Feed Additive Potassium Diformate PreventsAntibiotics (Basel, Switzerland) · 2022Article
- PhosphatidylethanolamineBiomolecules · 2022Article
- Application of Organic Acids and Essential Oils as Alternatives to Antibiotic Growth Promoters in Broiler Chickens.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Out of the alternatives to antibiotics and zinc oxide, organic acids, or simply acidifiers, play significant roles, especially in ensuring gut health and the growth performance of pigs. Regarding acidifiers, formic acid and its salts have shown very promising results in weaning, growing and finishing pigs. Although it is known that the main mechanisms by which acidifiers can improve livestock performance and health are related to the regulation of gastrointestinal pH, an improvement in intestinal digestibility and mineral utilization, and their antimicrobial properties against specific pathogens has been observed, while poor consensus remains in relation to the effect of acidifers on bacteria and the complex microbiome. Therefore, the aim of the present review was to critically evaluate the effects of formic acid and its salts on the performance and the gastrointestinal microbiota balance of pigs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.