Evidence map›Paper›PMID 32438708›Full record

ArticleNutrients2020

Proteomic and Metabolomic Correlates of Healthy Dietary Patterns: The Framingham Heart Study.

Maura E Walker, Rebecca J Song, Xiang Xu, Robert E Gerszten, Debby Ngo, Clary B Clish, Laura Corlin, Jiantao Ma, Vanessa Xanthakis, Paul F Jacques and 1 more

Abstract readEvaluation Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
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  5. Trial
  6. Trial
  7. Observational
  8. Article
  9. Article
  10. Proteomic Markers of Dietary Patterns, CKD Progression, and Mortality in the CRIC Study.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  11. Article
  12. Plasma Proteomic Profile of Dietary Potassium and Incident CKD.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maura E WalkerSection of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0001-9935-4113
Rebecca J SongDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Xiang XuDepartment of Mathematics and Statistics, Boston University College of Arts and Sciences, Boston, MA 02215, USA.ORCID 0000-0002-3446-2102
Robert E GersztenDivision of Cardiovascular Medicine Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Debby NgoDivision of Cardiovascular Medicine Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Clary B ClishBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Laura CorlinSection of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0002-3348-9063
Jiantao MaFramingham Heart Study, Framingham, MA 01702, USA.
Vanessa XanthakisSection of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
Paul F JacquesNutrition Epidemiology and Data Science, Tufts University Friedman School of Nutrition Science and Policy, Boston, MA 02111, USA.ORCID 0000-0001-5567-3147
Ramachandran S VasanSection of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
FRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · 2019 to 2024
$29.8M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1M
South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Jose E Cavazos · 2021 to 2026
$24.0M
PRECURSORS OF STROKE INCIDENCE AND PROGNOSISR01NS017950 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Hugo Javier Aparicio, Jose Rafael Romero · 1985 to 2026
$22.9M
Temporal Trends, Novel Imaging and Molecular Characterization of Preclinical and Clinical Alzheimer's Disease in the Framingham CohortsR01AG054076 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DECARLI, CHARLES, SESHADRI, SUDHA · 2016 to 2020
$12.3M
Cognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC)RF1AG059421 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2018 to 2018
$6.1M
Multidisciplinary Training Program in Cardiovascular EpidemiologyT32HL125232 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Matthew G. Nayor, Vanessa Xanthakis · 2016 to 2026
$5.0M
Lipid Biomarkers for Diabetic Heart DiseaseP20HL113444 · NHLBI · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 2012 to 2016
$4.7M
Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham StudyRF1AG063507 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GERSZTEN, ROBERT E, RAMACHANDRAN, VASAN S · 2019 to 2019
$4.2M
Proteomic Pathway Discovery in Cardiovascular DiseaseR01HL132320 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GERSZTEN, ROBERT E, RAMACHANDRAN, VASAN S · 2016 to 2019
$3.4M
CHARGE: Identifying Risk & Protective SNV for AD in ADSP Case-control SampleU01AG049505 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2014 to 2017
$3.0M
NHLBI NIH HHS 5T32HL125232NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268201500001INHLBI NIH HHS P20 HL113444NHLBI NIH HHS P30 DK020579NHLBI NIH HHS R01 HL132320NIA NIH HHS P30 AG066546NIA NIH HHS R01 AG054076NIA NIH HHS RF1 AG059421NIA NIH HHS RF1 AG063507NIA NIH HHS U01 AG049505NIA NIH HHS U01 AG052409NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK040561NINDS NIH HHS R01 NS017950
6 · The paper itself

Abstract

Data on proteomic and metabolomic signatures of healthy dietary patterns are limited. We evaluated the cross-sectional association of serum proteomic and metabolomic markers with three dietary patterns: the Alternative Healthy Eating Index (AHEI), the Dietary Approaches to Stop Hypertension (DASH) diet; and a Mediterranean-style (MDS) diet. We examined participants from the Framingham Offspring Study (mean age; 55 years; 52% women) who had complete proteomic (

Indexed as

MetabolomeCross-Sectional StudiesDietary Approaches To Stop HypertensionDiet, HealthyDiet, MediterraneanDiet SurveysEatingFemaleHumansLinear ModelsLongitudinal StudiesMaleMetabolomicsMiddle AgedProteomeProteomicsProteomebiomarkerdietary patternsdiet qualitymetabolomicproteomic

Identifiers

PMID32438708
PMCPMC7284467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.