Evidence map›Paper›PMID 32438699›Full record

ArticleAnimals : an open access journal from MDPI2020

Study of the Metabolomics of Equine Preovulatory Follicular Fluid: A Way to Improve Current In Vitro Maturation Media.

Pablo Fernández-Hernández, María Jesús Sánchez-Calabuig, Luis Jesús García-Marín, María J Bragado, Alfonso Gutiérrez-Adán, Óscar Millet, Chiara Bruzzone, Lauro González-Fernández, Beatriz Macías-García

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Oocyte and Embryo Vitrification in Horses.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Sperm Metabolomics through Nuclear Magnetic Resonance Spectroscopy.Animals : an open access journal from MDPI · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pablo Fernández-HernándezResearch Group of Intracellular Signaling and Technology of Reproduction, Research Institute INBIO G + C, University of Extremadura, 10003 Cáceres, Spain.
María Jesús Sánchez-CalabuigDepartment of Animal Reproduction, INIA, 28040 Madrid, Spain.
Luis Jesús García-MarínResearch Group of Intracellular Signaling and Technology of Reproduction, Research Institute INBIO G + C, University of Extremadura, 10003 Cáceres, Spain.
María J BragadoResearch Group of Intracellular Signaling and Technology of Reproduction, Research Institute INBIO G + C, University of Extremadura, 10003 Cáceres, Spain.
Alfonso Gutiérrez-AdánDepartment of Animal Reproduction, INIA, 28040 Madrid, Spain.
Óscar MilletPrecision Medicine and Metabolism Lab., CICbioGUNE, 48160 Vizcaya, Spain.
Chiara BruzzonePrecision Medicine and Metabolism Lab., CICbioGUNE, 48160 Vizcaya, Spain.
Lauro González-FernándezResearch Group of Intracellular Signaling and Technology of Reproduction, Research Institute INBIO G + C, University of Extremadura, 10003 Cáceres, Spain.
Beatriz Macías-GarcíaResearch Group of Intracellular Signaling and Technology of Reproduction, Research Institute INBIO G + C, University of Extremadura, 10003 Cáceres, Spain.
Universidad de Extremadura · ESCIC bioGUNE · ESUniversidad Complutense de Madrid · ES

Funding

Agencia Estatal de Investigación AGL2017-84681-RAgencia Estatal de Investigación RTI2018-093548-B-I00Agencia Estatal de Investigación RYC-2017-21545Junta de Extremadura TA18008Universidad de Extremadura Acción II Beca RC4
6 · The paper itself

Abstract

Production of equine embryos in vitro is currently a commercial technique and a reliable way of obtaining offspring. In order to produce those embryos, immature oocytes are retrieved from postmortem ovaries or live mares by ovum pick-up (OPU), matured in vitro (IVM), fertilized by intracytoplasmic sperm injection (ICSI), and cultured until day 8-10 of development. However, at best, roughly 10% of the oocytes matured in vitro and followed by ICSI end up in successful pregnancy and foaling, and this could be due to suboptimal IVM conditions. Hence, in the present work, we aimed to elucidate the major metabolites present in equine preovulatory follicular fluid (FF) obtained from postmortem mares using proton nuclear magnetic resonance spectroscopy (

Indexed as

equineIVMmetabolomicoocytes

Identifiers

PMID32438699
PMCPMC7278476
OpenAlexW3026320148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.