ArticleNanomaterials (Basel, Switzerland)2020
Electrospun PCL/PGS Composite Fibers Incorporating Bioactive Glass Particles for Soft Tissue Engineering Applications.
Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 66 citations in OpenAlex.
- Boron-Doped Mesoporous Bioactive Glass Nanoparticles (B-MBGNs) in Poly(ε-caprolactone)/Poly(propylene succinate-ACS applied bio materials · 2025Article
- Incorporation of Poly(propylene succinate-ACS applied bio materials · 2025Article
- Poly(glycerol succinate) hydrogel promotes spinal cord repair by regulating bio-energetic activity in severe injury.Materials today. Bio · 2025Article
- Physical properties of zinc, silver, or cerium ion doped borate glass incorporated PCL/gelatin electrospun fibers and their interaction with NG108-15 neural cells.Journal of materials science. Materials in medicine · 2025Article
- Development of Bioactive Hybrid Poly(lactic acid)/Poly(methyl methacrylate) (PLA/PMMA) Electrospun Fibers Functionalized with Bioglass Nanoparticles for Bone Tissue Engineering Applications.International journal of molecular sciences · 2024Article
- Article
- Recent Progress of Electrospun Herbal Medicine Nanofibers.Biomolecules · 2023Review
- Stress-Induced Intensification of Deoxyshikonin Production inPlants (Basel, Switzerland) · 2022Article
- Current Concepts and Methods in Tissue Interface Scaffold Fabrication.Biomimetics (Basel, Switzerland) · 2022Review
- One-Step Preparation of PVDF/GO Electrospun Nanofibrous Membrane for High-Efficient Adsorption of Cr(VI).Nanomaterials (Basel, Switzerland) · 2022Article
- Electrospun Polycaprolactone Nanofibers: Current Research and Applications in Biomedical Application.Advanced pharmaceutical bulletin · 2022Review
- Highlights on Advancing Frontiers in Tissue Engineering.Tissue engineering. Part B, Reviews · 2022Review
- Nanocomposite electrospun fibers of poly(ε-caprolactone)/bioactive glass with shape memory properties.Bioactive materials · 2022Article
- Different methods of synthesizing poly(glycerol sebacate) (PGS): A review.Frontiers in bioengineering and biotechnology · 2022Review
- Bioactive glass-based fibrous wound dressings.Burns & trauma · 2022Review
- Poly(Glycerol Sebacate) in Biomedical Applications-A Review of the Recent Literature.Advanced healthcare materials · 2021Review
- Scale-up of Electrospinning: Market Overview of Products and Devices for Pharmaceutical and Biomedical Purposes.Pharmaceutics · 2021Review
- Nature-Derived and Synthetic Additives to poly(ɛ-Caprolactone) Nanofibrous Systems for Biomedicine; an Updated Overview.Frontiers in chemistry · 2021Review
- Poly (Glycerol Sebacate)-Based Bio-Artificial Multiporous Matrix for Bone Regeneration.Frontiers in chemistry · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poly(glycerol-sebacate) (PGS) and poly(epsilon caprolactone) (PCL) have been widely investigated for biomedical applications in combination with the electrospinning process. Among others, one advantage of this blend is its suitability to be processed with benign solvents for electrospinning. In this work, the suitability of PGS/PCL polymers for the fabrication of composite fibers incorporating bioactive glass (BG) particles was investigated. Composite electrospun fibers containing silicate or borosilicate glass particles (13-93 and 13-93BS, respectively) were obtained and characterized. Neat PCL and PCL composite electrospun fibers were used as control to investigate the possible effect of the presence of PGS and the influence of the bioactive glass particles. In fact, with the addition of PGS an increase in the average fiber diameter was observed, while in all the composite fibers, the presence of BG particles induced an increase in the fiber diameter distribution, without changing significantly the average fiber diameter. Results confirmed that the blended fibers are hydrophilic, while the addition of BG particles does not affect fiber wettability. Degradation test and acellular bioactivity test highlight the release of the BG particles from all composite fibers, relevant for all applications related to therapeutic ion release, i.e., wound healing. Because of weak interface between the incorporated BG particles and the polymeric fibers, mechanical properties were not improved in the composite fibers. Promising results were obtained from preliminary biological tests for potential use of the developed mats for soft tissue engineering applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.