ReviewNutrients2020
Vitamin D Deficiency and Oral Health: A Comprehensive Review.
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 15 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 15 syntheses or guidelines pooled it, 243 citations in OpenAlex.
- Relative risk of oral manifestations with celiac disease: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- Effects of Maternal Vitamin D Supplementation on Childhood Health.Endocrine reviews · 2026Pooled it
- Analysis of the Additive Effects of Nutritional Strategies in Strength Training Interventions on Body Composition, Muscle Strength and Bone Mineral Density in Postmenopausal Women: A Systematic Review.Sports medicine - open · 2026Pooled it
- Effects of Maternal Vitamin D Supplementation on Childhood Health.Endocrine reviews · 2025Pooled it
- Influence of Vitamin D on Developmental Defects of Enamel (DDE) in Children and Adolescents: A Systematic Review.Nutrients · 2025Pooled it
- Vitamin D deficiency and oral health: a systematic review of literature.BMC oral health · 2025Pooled it
- Are low serum levels of Vitamin D associated with dental developmental defects in primary teeth? A systematic review.Evidence-based dentistry · 2024Pooled it
- Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.Oral health & preventive dentistry · 2024Pooled it
- Examining the Role of Vitamin D in Caries Susceptibility in Children's Deciduous Teeth: A Systematic Review.Nutrients · 2023Pooled it
- Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- The Impact of Prenatal Vitamin D on Enamel Defects and Tooth Erosion: A Systematic Review.Nutrients · 2023Pooled it
- Associations of Prenatal Vitamin D status with Oral Health in Offspring: A Systematic Review.Oral health & preventive dentistry · 2022Pooled it
- Obesity and oral health in Mexican children and adolescents: systematic review and meta-analysis.Nutrition reviews · 2022Pooled it
- Pooled it
- Nutritional Stunting Is Linked to Reduced Oral Microbiome Stability and Reconfigured Microbial Networks in Children: A Pilot Intervention Study.Pathogens (Basel, Switzerland) · 2026Trial
- Improving Parental Health Literacy in Primary Caregivers of 0- to 3-Year-Old Children Through a WeChat Official Account: Cluster Randomized Controlled Trial.JMIR public health and surveillance · 2024Trial
- Association between serum antibodies against oral microorganisms and vitamin D deficiency among US adults: A cross-sectional study.Medicine · 2026Article
- The effect of vitamin D supplementation on periodontal health: a systematic review and meta-analysis.Evidence-based dentistry · 2026Article
- Generalized Developmental Enamel Hypoplasia of the Permanent Dentition Associated with Early Childhood Vitamin D Deficiency Rickets: A Case Report.Dentistry journal · 2026Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D (VD) levels have been gaining growing attention in Oral Health. During growth and adulthood, VD deficiency (VDD) is associated with a wide variety of oral health disorders, and impaired VD synthesis may expedite some of these conditions. In children, severe VDD can induce defective tooth mineralization, resulting in dentin and enamel defects. As a consequence, these defects may increase the risk of the onset and progression of dental caries. Further, VDD has been associated with higher prevalence of periodontitis and gingival inflammation, and several recent preclinical and clinical studies have unveiled potential pathways through which Vitamin D may interact with the periodontium. VDD correction through supplementation may contribute to a successful treatment of periodontitis; however, alveolar bone regeneration procedures performed in baseline VDD patients seem more prone to failure. Vitamin D may also be linked with some oral pathology entities such as certain oral cancers and events of osteonecrosis of the jaw. This review aims to provide comprehensive evidence of how VD levels should be considered to promote good oral health, and to summarize how VDD may hamper oral development and its role in certain oral conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.