Evidence map›Paper›PMID 32438544›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Microcrystalline Cellulose Extracted from Native Plants as an Excipient for Solid Dosage Formulations in Drug Delivery.

Camila Viera-Herrera, Javier Santamaría-Aguirre, Karla Vizuete, Alexis Debut, Daniel C Whitehead, Frank Alexis

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Camila Viera-HerreraSchool of Biological Sciences and Engineering, Yachay Tech University, Urcuquí 100650, Ecuador.
Javier Santamaría-AguirreFaculty of Chemical Sciences, Universidad Central del Ecuador, Instituto de Investigación en Salud Pública y Zoonosis (CIZ), Quito 170130, Ecuador.ORCID 0000-0002-1683-5737
Karla VizueteCenter of Nanoscience and Nanotechnology, Universidad de las Fuerzas Armadas ESPE, Sangolquí 170501, Ecuador.ORCID 0000-0002-8912-5402
Alexis DebutCenter of Nanoscience and Nanotechnology, Universidad de las Fuerzas Armadas ESPE, Sangolquí 170501, Ecuador.ORCID 0000-0002-8269-7619
Daniel C WhiteheadDepartment of Chemistry, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0001-6881-2628
Frank AlexisSchool of Biological Sciences and Engineering, Yachay Tech University, Urcuquí 100650, Ecuador.
Universidad de las Fuerzas Armadas ESPE · ECUniversidad Yachay Tech · ECCentral University of Ecuador · ECClemson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excipients represent the complement of the active principle in any pharmaceutical form. Their function is to provide stability, protection, and to ensure absorption of the drug and acceptability in patients. Cellulose is a conventional excipient in many pharmaceutical solid dosage products. Most of the sources used to extract microcrystalline cellulose come from cotton or wood, which are expensive and in high demand from other industries. As plants are considered the main source of excipient production, we have taken advantage of the biodiversity of Ecuador to evaluate microcrystalline cellulose extracted from borojó (

Indexed as

cellulosedrug deliverypharmaceutical excipienttablets

Identifiers

PMID32438544
PMCPMC7712051
OpenAlexW3025637122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.