ArticleYeungnam University journal of medicine2020
Mineralization-inducing potentials of calcium silicate-based pulp capping materials in human dental pulp cells.
Article in Yeungnam University journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Pulpotomy in Primary Molars with Deep Caries Using Biodentine: A Case Series with 1-Year Follow-Up.Dentistry journal · 2026Article
- Calcium Silicate-Based Cements for Vital Pulp Therapy: Integrated Assessment of Radiopacity, Elemental Composition, and 24-h Pulp Cell Responses.Biomimetics (Basel, Switzerland) · 2026Article
- Resin-Modified Calcium Silicate-Based Materials Versus Conventional Formulations in Primary Teeth: A Systematic Review and Meta-Analysis of Clinical and Radiographic Outcomes of Vital Pulp Therapy Procedures in Pediatric Dentistry.Journal of functional biomaterials · 2026Review
- Article
- Fluorinated graphene-modified biodentine: an in vitro study on its ion release, cell growth, differentiation potential, and compressive strength.BMC oral health · 2025Article
- AnJournal of conservative dentistry and endodontics · 2025Article
- Physicochemical and antibacterial evaluation of novel nano α-TCP-AgNPs biocomposites for direct pulp-capping applications.Frontiers in oral health · 2025Article
- Effect of pulp capping materials on odontogenic differentiation of human dental pulp stem cells: An in vitro study.Clinical and experimental dental research · 2024Article
- Ion release, biocompatibility, and bioactivity of resin-modified calcium hydroxide cavity liners.BMC oral health · 2023Article
- Cytotoxicity of dental self-curing resin for a temporary crown: an in vitro study.Journal of Yeungnam medical science · 2023Article
- Ex Vivo Osteogenesis Induced by Calcium Silicate-Based Cement Extracts.Journal of functional biomaterials · 2023Article
- Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study.BMC oral health · 2023Article
- Present status and future directions: Hydraulic materials for endodontic use.International endodontic journal · 2022Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo provide a long-term bacterial seal through the formation of reparative dentin bridge, calcium silicate-based pulp capping materials have been used at sites of pulpal exposure. The aim of this study was to evaluate the mineralization-inducing potentials of calcium silicate-based pulp capping materials (ProRoot MTA [PR], Biodentine [BD], and TheraCal LC [TC]) in human dental pulp cells (HDPCs).
methodsSpecimens of test materials were placed in deionized water for various incubation times to measure the pH variation and the concentration of calcium released. The morphology of HDPCs cultured on the specimens was examined using a confocal laser scanning microscope (CLSM). Alizarin red S staining and alkaline phosphatase assays were used to evaluate mineralization-inducing potentials of the capping materials.
resultsBD showed the highest calcium release in all test periods, followed by PR and TC. (p<0.05). All experimental groups showed high alkalinity after 1 day, except at 14 days. BD showed the highest cell viability compared with PR and TC after 1 and 3 days, while TC showed the lowest value (p<0.05). The CLSM analysis showed that cells were well adhered and expressed actin filaments for all pulp capping materials. Mineralization by PR and BD groups was higher than that by TC group based on alizarin red S staining. BD showed significantly higher alkaline phosphatase activity than PR and TC, while TC showed the lowest value (p<0.05).
conclusionWithin the limitations of the in vitro study, BD had higher mineralization-inducing potential than PR and TC.
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