Evidence map›Paper›PMID 32438432›Full record

ArticleEuropean journal of dentistry2020

Evaluation of Osteocalcin Levels in Saliva of Periodontitis Patients and Their Correlation with the Disease Severity: A Cross-Sectional Study.

Hamda Shazam, Fouzia Shaikh, Zaheer Hussain, M Mansoor Majeed, Saba Khan, Zohaib Khurshid

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hamda ShazamDepartment of Oral Pathology, College of Dentistry, Ziauddin University, Karachi, Pakistan.
Fouzia ShaikhDepartment of Pathology, Ziauddin University, Karachi, Pakistan.
Zaheer HussainDepartment of Periodontology, Altamash Institute of Dental Medicine, Karachi, Pakistan.
M Mansoor MajeedDepartment of Oral Biology, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Saba KhanDepartment of Oral Pathology, College of Dentistry, Ziauddin University, Karachi, Pakistan.
Zohaib KhurshidProsthodontics and Implantology, College of Dentistry, King Faisal University, Al Ahsa, Kingdom of Saudi Arabia.ORCID 0000-0001-7998-7335
Ziauddin University · PKKarachi Medical and Dental College · PKKing Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe present study aimed to investigate osteocalcin levels in saliva of healthy and periodontitis patients and correlate these levels with periodontitis severity. MATERIALS AND

methodsThis cross-sectional study was conducted in a hospital setup. A total of 95 individuals participated in the study with 46 subjects in group I (healthy individuals) and 49 subjects in group II (mild, moderate, and severe chronic periodontitis patients). A detailed assessment of clinical periodontal parameters and alveolar bone loss was made. Unstimulated saliva samples were collected from all study subjects and osteocalcin levels were quantitatively analyzed by sandwich enzyme-linked immunosorbent essay technique. STATISTICAL ANALYSIS: One-way analysis of variance, Spearman's correlation test, and Pearson's chi-squared test were applied at a significance level of 95%.

resultsThe results showed a significant association of qualification with group II (

conclusionThe overall study results showed that there was no significant difference between saliva osteocalcin levels of healthy and periodontitis patients. Also, there was a nonsignificant correlation between osteocalcin levels and periodontitis severity. The findings of the present study support the hypothesis that low osteocalcin levels in saliva might be considered as a poor indicator of periodontal disease progression and severity.

Identifiers

PMID32438432
PMCPMC7440941
OpenAlexW3026212274

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.