ReviewEuropean journal of endocrinology2020
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of hyperthyroidism and hypothyroidism.
Review in European journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Pediatric endocrinopathies related to COVID-19: an update.World journal of pediatrics : WJP · 2023Pooled it
- Thyroid surgery during the COVID-19 pandemic: results from a systematic review.Journal of endocrinological investigation · 2022Pooled it
- Causal associations between thyroid dysfunction and COVID-19 susceptibility and severity: A bidirectional Mendelian randomization study.Frontiers in endocrinology · 2022Pooled it
- Changes in nationwide thyroid hormone replacement use during the pandemic: results from the Trends in Drug Utilization During COVID-19 Pandemic in Turkey (PANDUTI-TR) Study.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Familial Risk of Hashimoto's Thyroiditis in a Large Genealogical Database.The Journal of clinical endocrinology and metabolism · 2025Article
- British Thyroid Association Survey of Graves' Disease Management in the UK.Clinical endocrinology · 2025Article
- Increased incidence of myxedema coma during the COVID-19 pandemic and in the post pandemic era: a single-center case series.Internal and emergency medicine · 2024Article
- Review
- Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024Review
- Impact of COVID-19 pandemic on thyroidectomy for malignant diseases in high-volume referral centers.Updates in surgery · 2024Article
- The Influence of Autoimmune Thyroid Diseases on Viral Pneumonia Development, Including COVID-19: A Two-Sample Mendelian Randomization Study.Pathogens (Basel, Switzerland) · 2024Article
- The effect of COVID-19 process on patients with endocrinological disease in a pandemic hospital: What happened to the others?Archives of endocrinology and metabolism · 2023Article
- Differences in the clinical picture at the onset of diagnosis of severe autoimmune hypothyroidism in children depending on the time of diagnosis: before or during the SARS-CoV-2 pandemic.Pediatric endocrinology, diabetes, and metabolism · 2023Article
- Metformin is associated with reduced COVID-19 severity in patients with prediabetes.Diabetes research and clinical practice · 2022Observational
- Metformin is Associated with Reduced COVID-19 Severity in Patients with Prediabetes.medRxiv : the preprint server for health sciences · 2022Article
- Remote management of osteoporosis in the first wave of the COVID-19 pandemic.Archives of osteoporosis · 2022Article
- Potential relationships between COVID-19 and the thyroid gland: an update.The Journal of international medical research · 2022Review
- Delayed Follow-up Visits and Thyrotropin Among Patients With Levothyroxine During the COVID-19 Pandemic.Journal of the Endocrine Society · 2022Article
- The Effect of Inactivated SARS-CoV-2 Vaccines on TRAB in Graves' Disease.Frontiers in endocrinology · 2022Article
- COVID-19 and thyroid function: What do we know so far?Frontiers in endocrinology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This manuscript provides guidance on the management of thyroid dysfunction during the COVID-19 pandemic. Autoimmune thyroid diseases are not linked to increased risks of COVID-19. Uncontrolled thyrotoxicosis may result in more severe complications from SARS-CoV-2 infection, including thyroid storm. The management of patients with a new diagnosis of hyperthyroidism is best undertaken with a block-and-replace regimen due to limited biochemical testing availability. Antithyroid drug (ATD)-induced neutropenia may favour the progression of COVID-19 and symptoms of infection may be confused with SARS-CoV-2 infection. The withdrawal of ATDs and urgent measurement of neutrophils should be considered in case of flu-like manifestations occurring in the initial months of treatment. Urgent surgery or 131-I may be undertaken in selected cases of uncontrolled thyrotoxicosis. Patients with COVID-19 infection may present with conjunctivitis, which could cause diagnostic difficulties in patients with new or existing Graves' ophthalmopathy. Patients who are on replacement treatment with thyroid hormones should ensure they have sufficient supply of medication. The usual advice to increase dosage of levothyroxine during pregnancy should be adhered to. Many newly presenting and previously diagnosed patients with thyroid dysfunction can be managed through virtual telephone or video clinics supported by a dedicated nurse-led service, depending on available facilities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.