ArticleiScience2020
Genomic Blueprint of Glycine Betaine Metabolism in Coral Metaorganisms and Their Contribution to Reef Nitrogen Budgets.
Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Coral metabolomic diversity is associated with restoration success.Scientific reports · 2026Article
- Identification of a membrane transporter for dimethylsulfoniopropionate uptake in marine eukaryotic phytoplankton.Nature communications · 2026Article
- Adaptive metabolic reprogramming conserves energy status in Antarctic giants.Scientific reports · 2026Article
- Article
- Dual roles of glycine betaine, dimethylglycine, and sarcosine as osmoprotectants and nutrient sources forApplied and environmental microbiology · 2025Article
- Transcriptomic insights into the low-salinity tolerance of the sea louse Caligus elongatus.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Article
- The coral microbiome in sickness, in health and in a changing world.Nature reviews. Microbiology · 2024Review
- Unlocking the genomic potential of Red Sea coral probiotics.Scientific reports · 2024Article
- Mitigation ofApplied and environmental microbiology · 2024Article
- A genome-centric view of the role of the Acropora kenti microbiome in coral health and resilience.Nature communications · 2024Article
- Intersection of coral molecular responses to a localized mortality event and ex situ deoxygenation.Ecology and evolution · 2024Article
- Future ocean conditions induce necrosis, microbial dysbiosis and nutrient cycling imbalance in the reef sponge Stylissa flabelliformis.ISME communications · 2023Article
- Exploring the Potential Molecular Mechanisms of Interactions between a Probiotic Consortium and Its Coral Host.mSystems · 2023Article
- Red Sea Atlas of Coral-Associated Bacteria Highlights Common Microbiome Members and Their Distribution across Environmental Gradients-A Systematic Review.Microorganisms · 2022Review
- Microbiome Restructuring: Dominant Coral BacteriummSystems · 2022Article
- Coral holobiont cues prime Endozoicomonas for a symbiotic lifestyle.The ISME journal · 2022Article
- Intrapopulation adaptive variance supports thermal tolerance in a reef-building coral.Communications biology · 2022Article
- Glycine betaine uptake and metabolism in marine microbial communities.Environmental microbiology · 2022Article
- Contrasting Microbiome Dynamics of Putative Denitrifying Bacteria in Two Octocoral Species Exposed to Dissolved Organic Carbon (DOC) and Warming.Applied and environmental microbiology · 2022Article
- Naturally occurring fire coral clones demonstrate a genetic and environmental basis of microbiome composition.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The osmolyte glycine betaine (GB) ranks among the few widespread biomolecules in all three domains of life. In corals, tissue concentrations of GB are substantially higher than in the ambient seawater. However, the synthetic routes remain unresolved, questioning whether intracellular GB originates from de novo synthesis or heterotrophic input. Here we show that the genomic blueprint of coral metaorganisms encode the biosynthetic and degradation machinery for GB. Member organisms also adopted the prokaryotic high-affinity carrier-mediated uptake of exogenous GB, rendering coral reefs potential sinks of marine dissolved GB. The machinery metabolizing GB is highly expressed in the coral model Aiptasia and its microalgal symbionts, signifying GB's role in the cnidarian-dinoflagellate symbiosis. We estimate that corals store between 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.